CLINICAL BENEFITS OF MILK THISTLE (SILYBUM MARIANUM): A RECENT REVIEW
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 1
Abstract
Milk thistle (Silybum marianum) has been used for 2,000 years as an herbal remedy for a variety of ailments, particularly liver, kidney, and gall bladder problems. Milk thistle is widely used in Europe for hepatic and biliary disorders, and is beginning to be used to protect against nephrotoxicity as well. It protects the liver from several hepatotoxins, including Amanita mushrooms, acetaminophen and alcohol. Its primary active ingredient is silymarin, which has antioxidant and anti-inflammatory properties, and it may help the liver repair itself by growing new cells. Several scientific studies suggest that substances in milk thistle (especially a flavonoid called silymarin) protect the liver from toxins, including certain drugs such as acetaminophen (Tylenol), which can cause liver damage in high doses. Its leaves, flowers and roots have historically been considered a vegetable in European diets, and its fruits (achenes), which resemble seeds, have been roasted for use as a coffee substitute. The leaves of the plant are eaten in fresh salads and as spinach substitute, the stalks eaten like asparagus, and the flower heads served as one would an artichoke.
Authors and Affiliations
Patel Chirag J*| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020., Prof. Satyanand Tyagi| President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India-110074., Umesh Kumar| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020., Patel Shreya| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020., Patel Pinkesh| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020., Chaudhari Bharat| Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
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