Gingival Leiomyosarcoma in a Young Woman Case report and literature review
Journal Title: Sultan Qaboos University Medical Journal - Year 2017, Vol 17, Issue 4
Abstract
Leiomyosarcoma (LMS) is a rare mesenchymal malignancy, of which 3–10% of cases occur in the head and neck region. We report a 22-year-old woman who was referred to the University Hospital of Siena, Italy, in 2016 with an ostensibly benign asymptomatic lump on the mandibular gingiva. Te lesion grew rapidly, causing otalgia in the right ear. An excisional biopsy was performed and primary LMS was diagnosed histologically. Subsequently, the patient underwent radical re-excision of the perilesional mucosa, a partial bone resection and the extraction of four teeth. No recurrences or metastases were detectable at a 20-month follow-up. Tis report discusses the differential diagnosis of LMS with regards to other benign and malignant lesions and reviews the recent literature on primary and secondary oral LMS. Due to its innocuous clinical features—including its asymptomatic nature and presentation at a young age—this aggressive malignancy can go undetected; therefore, an early histopathological diagnosis is crucial.
Authors and Affiliations
Massimo Viviano| Department of Dentistry & Ophthalmology, University of Siena, Siena, Italy, Clelia Miracco| Department of Pathological Anatomy, University of Siena, Siena, Italy, Guido Lorenzini| Department of Medical Biotechnology, University of Siena, Siena, Italy, Gennaro Baldino| Department of Pathological Anatomy, University of Siena, Siena, Italy, Serena Cocca| Department of Ear, Nose & Throat, University of Siena, Siena, Italy
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- EP ID EP14828
- DOI 10.18295/squmj.2017.17.04.017
- Views 305
- Downloads 14
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