The study of burn healing of Onosma stenosiphon on type II burn of back and testis areas in rats

Journal Title: Journal of Herbal Drugs - Year 2010, Vol 1, Issue 1

Abstract

Background & Aim: Onosma stenosiphon has been used as herbal medicine for healing skin cuts and rashes. However, burn healing effect of this herb has not been yet reported in pharmaceutical texts. The aim of this study was to find out the effect of herb ointment on burn healing the superficial wounds post type II burns of back and testis region in Wistar rats. Experimental: A total of 24 rats were divided into 3 (21 rats) and 1 control (3 rats) groups. Type II burn was performed on right and left sides of back and right testicular skin of all experimental animals. For burn healing, herb ointment was applied on right sides of back and testis skins of experimental rats. For histo-pathological evaluation, seven rats were killed at 7, 14, 21 days intervals. Then, skin samples were obtained from both left and right (with herb ointment) sides of back, as well as testicular tissue samples. All samples from experimental animals were compared with control samples following tissue staining. Results & Discussion: All skin samples (both with and without herb ointment applications) showed patho-morphological changes one week post experimental burns. Two week following burns, epidermis were relatively healed, and lymphohistocytological inflammation with initiation of fibrosis was observed. But, epidermis and dermis inflammation were recovered after three weeks. There were no noticeable changes in healing rate of burned tissues in rats under herb ointment versus non ointment applications. Also, there were no alternations in testicular tissue or spermatozoa cells in experimental groups.

Authors and Affiliations

Mohammad Ali Khalili; Seyad Mohsen Miresmaeili; Hosein Hekmati Moghaddam; Shahnaz Rezaei; Ali Reza Vahidi

Keywords

Related Articles

Determination of alkaloids amount from Iranian Papaver bracteatum Lindl. by HPLC

Background & Aim: Papaver bracteatum Lindl. (Papaverace) is an important pharmaceutical plant which contains isoqinoline alkaloids. Isoqinoline alkaloids constitute one distinct group of secondary metabolites of the Pap...

Systematically study of medicinal plants in Bushehr province, Southern Iran

Background & Aim: Bushehrwith an area of about 177.1kmĀ² is situated in center of Bushehr province, southern Iran. Existence beach line with Persian gulf and Helle river cause of settlement diversity in this zone. With at...

Effect of milk thistle on the immune system, intestinal related variables, appearance and mortality of broilers contaminated with Aflatoxin B1

Background & Aim: Aflatoxin (AF) is the most important fungus that contaminates food and feed and can enter the food chain of humans. The aim of this study was to investigate the ability of thistle seeds (silybum marianu...

Effect of alcoholic extract of Sheng and Ziziphora medicinal plants on physico-chemical properties and microbial quality of set yogurt

Background & Aim: Natural compounds can prolong the shelf life of food by inhibiting the growth of pathogenic and spoilage microorganisms. The purpose of this study was to investigate the effect of Sheng and Ziziphora al...

Phytochemical of essential oil of Stachys lavandulifolia Vahl. collected from a natural habitat in western Isfahan, Iran

Background & Aim: The Lamiaceae family is one of the largest and most distinctive families of flowering plants, with about 220 genera and almost 4000 species worldwide. The genus Stachys is one of the largest represen...

Download PDF file
  • EP ID EP23305
  • DOI -
  • Views 544
  • Downloads 90

How To Cite

Mohammad Ali Khalili; Seyad Mohsen Miresmaeili; Hosein Hekmati Moghaddam; Shahnaz Rezaei; Ali Reza Vahidi (2010). The study of burn healing of Onosma stenosiphon on type II burn of back and testis areas in rats. Journal of Herbal Drugs, 1(1), -. https://europub.co.uk/articles/-A-23305