FORMULATION AND EVALUATION OF ETODOLAC NIOSOMES BY MODIFIED ETHER INJECTION TECHNIQUE
Journal Title: Universal Journal of Pharmaceutical Research - Year 2016, Vol 1, Issue 1
Abstract
Etodolac is an indole acetic acid derivative with half-life of 4 to 7 hrs. It is used for the treatment of Rheumatoid arthritis. Whenever used orally, it has many systemic side effects, so it is not preferred orally. In present study four niosomes formulations of Etodolac were successfully developed by modified ether injection technique using different nonionic surfactant i.e. Span 20, Span 40, Tween 20, Tween 40 and cholesterol. Formulations were evaluated for different parameters like particle size, entrapment efficiency, in-vitro release, stability studies.
Authors and Affiliations
Ejiogu Deborah Chioma
DESIGN AND EVALUATION OF CARBAMAZEPINE LOZENGES
Lozenges are the flavoured solid, unit dosage medicated dosage forms usually in the sweetened base intended to be sucked and held in the mouth or pharynx containing one or more medicaments. Lozenges were developed in 20...
EPIDEMICITY OF VIBRIO CHOLERA IN SANA’A CITY, YEMEN: PREVALENCE AND POTENTIAL DETERMINANTS
In 2017, a total of 889854 suspected cholera cases with 2578 deaths were reported from Yemen, thus WHO considered these figures to be the worst epidemic of cholera in recent history of humanity. The aims of the study we...
EFFECT AND MECHANISM OF TRADITIONAL CHINESE MEDICINE HUOLOU GUKANG PILL COMBINED WITH SIMVASTATIN ON STEROID-INDUCED NECROSIS OF FEMORAL HEAD
Aim of present study was to explore the effect and mechanism of traditional Chinese medicine HuoLou Gukang pill combined with simvastatin on steroid-induced necrosis of femoral head. A total of 130 patients with stero...
DEVELOPMENT AND IN-VITRO EVALUATION OF MATRIX-TYPE TRANSDERMAL PATCHES OF LOSARTAN POTASSIUM
Since last decade drugs through skin has received great attention of many researchers. The aim of present study was designed to develop a suitable matrix type transdermal drug delivery system (TDDS) of Losartan potassium...
ANTIMICROBIALS SELF MEDICATION AMONG PARAMEDICAL STUDENTS IN A NIGERIAN UNIVERSITY
Self-medication refers to selection and use of medicines by individuals to treat self-recognized illness and symptoms. It is widely practiced globally and often regarded as part of self-care. Though, unlike the other el...