ANTI-INFLAMMATORY AND ANTI-OXIDANT ACTIVITIES OF METHANOL EXTRACT OF BAPHIA NITIDA

ANTI-INFLAMMATORY AND ANTI-OXIDANT ACTIVITIES OF METHANOL EXTRACT OF BAPHIA NITIDA

Journal

Subject and more

  • LCC Subject Category: Medicine
  • Publisher's keywords: Baphia nitida, anti-oxidant, anti-inflammatory, carrageenan-induced paw edema
  • Language of fulltext: english
  • Full-text formats available: PDF

AUTHORS

    Deborah Ejiogu Chioma

EDITORIAL INFORMATION

FULL TEXT

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ABSTRACT

Baphia nitida is a tropical plant used in African folkloric medicine for the treatment of infections and inflammatory conditions. This study therefore seeks to investigate the biological activities including antioxidant and anti-inflammatory properties of leaf and root methanol extracts of B. nitida. Anti-inflammatory activities of extract was investigated by the carrageenan-induced paw edema model of inflammation, respectively. The antioxidant properties of the extracts as determined by the DPPH free radical scavenging assay. The leaves and root extract demonstrated potent anti-inflammatory activity at low concentrations of between 25-75 mg/kg body weight.

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