ANTI-INFLAMMATORY AND ANTI-OXIDANT ACTIVITIES OF METHANOL EXTRACT OF BAPHIA NITIDA
Journal Title: Universal Journal of Pharmaceutical Research - Year 2016, Vol 1, Issue 2
Abstract
Baphia nitida is a tropical plant used in African folkloric medicine for the treatment of infections and inflammatory conditions. This study therefore seeks to investigate the biological activities including antioxidant and anti-inflammatory properties of leaf and root methanol extracts of B. nitida. Anti-inflammatory activities of extract was investigated by the carrageenan-induced paw edema model of inflammation, respectively. The antioxidant properties of the extracts as determined by the DPPH free radical scavenging assay. The leaves and root extract demonstrated potent anti-inflammatory activity at low concentrations of between 25-75 mg/kg body weight.
Authors and Affiliations
Deborah Ejiogu Chioma
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