AN EXHAUSTIVE STATISTIC ON CURRENT MUCOADHESIVE INTRAVAGINAL DRUG DELIVERY METHODOLOGIES
Journal Title: Universal Journal of Pharmaceutical Research - Year 2017, Vol 2, Issue 6
Abstract
The vaginal course of medication conveyance offers many focal points because of its huge permeation range, rich vascularization, avoidance of first pass metabolism and relatively low enzymatic activity. A few examinations have demonstrated that for sedate organization the vaginal pit is a viable course which expected for the most part for neighborhood activity and conveying drugs for foundational impacts with uterine focusing on. It was first Sobrero who endeavored the vaginal mucosa for tranquilize assimilation, from that point forward much research has been done on the organization of medications through this course. As of late, for vaginal dose frame, different plan and application has expanded impressively. It is fundamentally the conveyance of medications inside or through the vaginal mucosa for neighborhood or foundational pharmacological activity. Degree of medication ingestion and its rate after organization may shift contingent upon vaginal physiology, age of the patient, arrange in the menstrual cycle, neurotic conditions and detailing factors. Here in this audit, there’s a feature, the advantages and confinements of vaginal medication conveyance, philosophy in assessment of vaginal medication conveyance frameworks, pharmaceutical viewpoints and an outline of late advances made in the bailiwick of vaginal medication conveyance. Advancement of measurements frame in various stages and in the market, are likewise audited.
Authors and Affiliations
Abhijeet Ojha, NVS Madhav, Shubham Tyagi, Vidhya Basnet, Hiba Parveen
Keywords
Related Articles
- EP ID EP36433
- DOI https://doi.org/10.22270/ujpr.v2i6.RW3
- Views 267
- Downloads 0
A REVIEW ON CONSTITUENTS, PHARMACOLOGICAL ACTIVITIES AND MEDICINAL USES OF GLYCYRRHIZA GLABRA
Plants have been one of the important sources of medicines for human being and animals since the ancient time. At present scenario there is an increasing demand for herbal medicines, health products and pharmaceuticals p...
SOLID DISPERSION- STRATEGY TO ENHANCE SOLUBILITY AND DISSOLUTION OF POORLY WATER SOLUBLE DRUGS
Improving oral bioavailability of drugs those given as solid dosage forms remains a challenge for the formulation scientists due to solubility problems. Over the years a variety of solubilization techniques have been stu...
Editorial Message...
It is great honor and high pleasure to be appointed as member- Editorial Board, then as executive editor, Universal Journal of Pharmaceutical Research (UJPR). My heartiest salutations and warm congratulation to all edito...
FORMULATION AND EVALUATION OF FINASTERIDE SUSTAINED-RELEASE MATRIX TABLETS USING DIFFERENT RATE CONTROLLING POLYMERS
The aim of the present investigation was to develop oral controlled release matrix tablet formulations of Finasteride with different polymer ratios. Finasteride is chemically considered a synthetic 4-azasteroid drug. The...
FORMULATION AND EVALUATION OF ETODOLAC NIOSOMES BY MODIFIED ETHER INJECTION TECHNIQUE
Etodolac is an indole acetic acid derivative with half-life of 4 to 7 hrs. It is used for the treatment of Rheumatoid arthritis. Whenever used orally, it has many systemic side effects, so it is not preferred orally. In...