EVALUATION OF ANTIBACTERIAL RESISTANCE OF BIOFILM FORMS OF AVIAN SALMONELLA GALLINARUM TO FLUOROQUINOLONES
Journal Title: Universal Journal of Pharmaceutical Research - Year 2018, Vol 3, Issue 4
Abstract
Antimicrobial resistance is a growing concern worldwide. The indiscriminate use of antibiotics for a period of time has led to the emergence of antibiotic resistance in pathogenic bacteria. The present study was designed to evaluate the antibacterial efficacy of fluoroquinolone drugs, ciprofloxacin, enrofloxacin, moxifloxacin, sparfloxacin, norfloxacin, pefloxacin and ofloxacin against avian Salmonella gallinarum bacterial biofilms. The study parameters, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and biofilm elimination concentration (BEC) were determined on days 1, 3, 7, 10, 14 and 20 post inoculation for the planktonic (free) and biofilm cells of S. gallinarum by macro broth dilution method. The MIC and MBC values determined on days 1, 3, 7, 10, 14 and 20 for each of the fluoroquinolone drugs against the planktonic and biofilm forms of avian S. gallinarum were found to be non-significant. BEC values determined against the biofilm forms of S. gallinarum during the study period were found to be non-significant among the tested fluoroquinolones. The results of the present study demonstrated that fluoroquinolone drugs were effective in vitro against both the planktonic and biofilm forms of avian S. gallinarum.
Authors and Affiliations
Kumar Kamashi, Mr. Honnegowda, Mayanna Asha, Chandrakala Ms.
Keywords
Related Articles
- EP ID EP36473
- DOI https://doi.org/10.22270/ujpr.v3i4.175
- Views 290
- Downloads 0
FORMULATION AND EVALUATION OF METOCLOPRAMIDE HCL RECTAL SUPPOSITORIES
Metoclopramide hydrochloride is a dopamine receptor antagonist, used mostly for stomach and esophageal problems as it is a prokinetic agent. The aim of the present study was to design and evaluate the suppositories of Me...
THE PREVALENCE AND PHENOTYPIC CHARACTERIZATION OF EXTENDED-SPECTRUM β-LACTAMASES-PRODUCING ESCHERICHIA COLI STRAINS ISOLATES RECOVERED FROM TERTIARY HOSPITALS IN SANA'A CITY, YEMEN
The emergence of ESBL producing Escherichia coli in clinical isolates is posing a serious threat for treating nosocomial infections. The aim of the study was to determine the frequency of extended spectrum β-lactamase (E...
Message.
''It’s been an inspiring journey serving as the Managing Editor of the Universal Journal of Pharmaceutical Research (UJPR) and I have all the editors, contributors and authors to thank for it. Universal Journal of Pha...
AN UPDATED REVIEW ON TRANSFERSOMES: A NOVEL VESICULAR SYSTEM FOR TRANSDERMAL DRUG DELIVERY
Transdermal route is an interesting option in this respect because a transdermal route is convenient and safe, avoid first pass metabolism, predictable and extended duration of activity, minimizing undesirable side effec...
A REVIEW ON CONSTITUENTS, PHARMACOLOGICAL ACTIVITIES AND MEDICINAL USES OF GLYCYRRHIZA GLABRA
Plants have been one of the important sources of medicines for human being and animals since the ancient time. At present scenario there is an increasing demand for herbal medicines, health products and pharmaceuticals p...