The study focused on factors influencing involvement of peri-urban farmers in mini-livestock farming in South-Western Nigeria. Specifically, the peri-urban farmers’ socio-economic characteristics were described, their level of involvement in rearing mini-livestock were determined and constraint associated with mini-livestock farming were examined. 182 respondents were interviewed through the use of structured interview schedule and Focus Group Discussions (FGDs). Data analysis was carried out using frequency counts, percentage, and factor analysis. The results of the study showed that more males were involved in mini-livestock rearing than females, while the mean age of a farmer was 46 years. Majorities were literate and information sourced from fellow farmers was most common and reliable source of information accessible by the respondents, while there was low extension contact. Problems confronting the respondents include inadequate credit facilities, untimely supply of inputs, improper management skill and low extension contacts. Results of the factor analysis revealed eleven factors which contributed to farmers’ involvement in mini-livestock farming. These include community influence, farmland acquisition, characteristics of mini-livestock, personality factor, and economic status. Other factors were capacity building, household composition,external orientation, farm characteristics, social group orientation and communication tool. The study concluded that policy making on mini-livestock development should focus at enhancing the socio-economic status of peri-urban farmers through improved to access to credit facilities and capacity building through training on improved management practice. This could have a profound influence on increased production, sustainable livelihood and alleviation of poverty among the populace.