Sultan Qaboos University Medical Journal

Sultan Qaboos University Medical Journal

Basic info

  • Publisher: Sultan Qaboos University
  • Country of publisher: oman
  • Date added to EuroPub: 2017/Sep/12

Subject and more

  • LCC Subject Category: Biochemistry, Biomedicine, Medicine
  • Publisher's keywords: Medicine, Biomedicine, Community Health, Family Medicine, Health Sciences, Biochemistry
  • Language of fulltext: english
  • Full-text formats available: PDF

Publication charges

  • Article Processing Charges (APCs): No
  • Submission charges: No
  • Waiver policy for charges? No

Editorial information

Open access & licensing

  • Type of License: CC BY
  • License terms
  • Open Access Statement: Yes
  • Year open access content began: 1999
  • Does the author retain unrestricted copyright? False
  • Does the author retain publishing rights? False

Best practice polices

  • Permanent article identifier: DOI
  • Content digitally archived in: LOCKSS
  • Deposit policy registered in: None

This journal has '1136' articles

The Accuracy of the Broselowâ„¢ Pediatric Emergency Tape for Weight Estimation in an Omani Paediatric Population

The Accuracy of the Broselowâ„¢ Pediatric Emergency Tape for Weight Estimation in an Omani Paediatric Population

Authors: Azher A. Al-Busaidi| Department of Emergency Medicine, Rustaq Hospital, Rustaq, Oman, Lakshmanan Jeyaseelan| Departments of Statistics & Health Inform...
( 16 downloads)
Abstract

Objectives: Tis study aimed to evaluate the accuracy of the Broselow™ Pediatric Emergency Tape (BT) for estimating weight in an Omani paediatric population at a tertiary care hospital. Methods: Tis retrospective cross-sectional study was conducted during July 2015. Te electronic medical records of Omani outpatients <14 years old attending the Sultan Qaboos University Hospital, Muscat, Oman, between July 2009 and June 2013 were reviewed for recorded height and weight data. Te BT Version 2002A was used to predict weight based on actual height measurements. Predicted weight measurements were then compared with actual weight to determine the accuracy of the estimation. Results: A total of 3,339 children were included in the study, of which 43.5% were female and 56.5% were male. Te mean age was 6.4 ± 3.1 years and the mean height was 93.2 ± 23.5 cm. Te mean actual weight was 13.9 ± 6.7 kg while the mean BT-predicted weight was 14.4 ± 6.9 kg. Te BT-predicted weight estimations correlated signifcantly with actual weight measurements (intraclass correlation coefcient: 0.97; P <0.001). A Bland-Altman analysis indicated that the BT performed well when estimating weight among Omani children, with an overestimation of only 0.5 kg for the entire cohort. Conclusion: Te BT was found to be an effective tool for estimating weight according to body length in an Omani paediatric population. It should therefore be considered for use in emergency situations when actual weight cannot be determined.

Keywords: Paediatrics, Body Weight, Body Height, Emergency Medicine, Oman
Outcomes of Multi-Trauma Road Traffc Crashes at a Tertiary Hospital in Oman Does attendance by trauma surgeons versus non-trauma surgeons make a difference?

Outcomes of Multi-Trauma Road Traffc Crashes at a Tertiary Hospital in Oman Does attendance by trauma surgeons versus non-trauma surgeons make a difference?

Authors: Ammar Al-Kashmiri| Department of Emergency Medicine, Khoula Hospital, Muscat, Oman, Sultan Z. Al-Shaqsi| Division of Plastic & Reconstructive Surgery,...
( 17 downloads)
Abstract

Objectives: Trauma surgeons are essential in hospital-based trauma care systems. However, there are limited data regarding the impact of their presence on the outcome of multi-trauma patients. Tis study aimed to assess the outcomes of multi-trauma road trafc crash (RTC) cases attended by trauma surgeons versus those attended by non-trauma surgeons at a tertiary hospital in Oman. Methods: Tis retrospective study was conducted in December 2015. A previously published cohort of 821 multi-trauma RTC patients admitted between January and December 2011 to the Sultan Qaboos University Hospital, Muscat, Oman, were reviewed for demographic, injury and hospitalisation data. In-hospital mortality constituted the main outcome, with admission to the intensive care unit, operative management, intubation and length of stay constituting secondary outcomes. Results: A total of 821 multi-trauma RTC cases were identifed; of these, 60 (7.3%) were attended by trauma surgeons. Tere was no signifcant difference in mortality between the two groups (P = 0.35). However, patients attended by trauma surgeons were signifcantly more likely to be intubated, admitted to the ICU and undergo operative interventions (P <0.01 each). Te average length of hospital stay in both groups was similar (2.6 versus 2.8 days; P = 0.81). Conclusion: No difference in mortality was observed between multi-trauma RTC patients attended by trauma surgeons in comparison to those cared for by non-trauma surgeons at a tertiary centre in Oman.

Keywords: Multiple Trauma, Resuscitation, Patient Outcome Assessment, Surgeons, Trauma Centers, Oman
Gender Differences in Heart Rate Variability Among Individuals Undergoing Regular Resistance Training Preliminary observations

Gender Differences in Heart Rate Variability Among Individuals Undergoing Regular Resistance Training Preliminary observations

Authors: Ellen S. V. Ramalho| Department of Biotechnology, Universidade Federal da Paraíba, Joao Pessoa, Brazil, Estevam L. Souza-Junior| Department of Biotech...
( 21 downloads)
Abstract

Objectives: Frequency-domain analysis of heart rate variability (HRV) is an effective tool to evaluate autonomic balance. Tis study aimed to investigate gender differences in HRV among individuals undergoing regular resistance training. Methods: Tis preliminary cross-sectional study was conducted from April to September 2016 in João Pessoa, Paraíba, Brazil. Te low-frequency (LF), high-frequency (HF) and LF/HF ratio components of HRV spectral analysis were analysed among 22 men and 27 women undergoing regular resistance training. Results: Among the male participants, the LF component was signifcantly increased compared to females in both the supine (1,171 ± 192 versus 545 ± 74 ms2; P = 0.0067) and upright (1,824 ± 260 versus 738 ± 133; P = 0.0011) positions. Te LF/HF ratio was also signifcantly increased in both positions among male participants (P <0.0500 each). Conclusion: Tese preliminary data suggest a possible gender difference in the HRV of individuals undergoing resistance training.

Keywords: Sympathetic Nervous System, Balance, Gender, Exercise, Resistance Training, Brazil
Discrimination Between Drug Abuse and Medical Therapy Case report of a tranylcypromine overdose-related fatality

Discrimination Between Drug Abuse and Medical Therapy Case report of a tranylcypromine overdose-related fatality

Authors: Maryam Akhgari| Department of Forensic Toxicology, Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran, Farzaneh Jokar| Departme...
( 15 downloads)
Abstract

Tranylcypromine is an effective antidepressant from the class of monoamine oxidase inhibitors and is structurally related to amphetamine. However, reports differ regarding the potential metabolism of tranylcypromine to amphetamine and methamphetamine within the human body. We report a 25-year-old woman with severe depression who died due to a fatal tranylcypromine overdose in 2016. She had been prescribed tranylcypromine one day previously and had no history of previous suicide attempts or substance abuse. Te body was transferred to a forensic medicine department in Tehran, Iran for the autopsy. A urine sample was positive for tranylcypromine, amphetamine and methamphetamine using gas chromatography/mass spectrometry after derivatisation with heptafluorobutyric acid. As amphetamines were present in the urine sample, it was assumed that the tranylcypromine had been converted to amphetamines metabolically. As such, it is possible that the legitimate use of certain prescription drugs may complicate the interpretation of test results for illegal drugs.

Keywords: Tranylcypromine, Amphetamine, Metabolism, Forensic Toxicology, Substance Abuse Detection, Case Report
Late Diagnosis of 5-α-Reductase Type 2 Defciency in an Adolescent Girl with Primary Amenorrhoea Case report

Late Diagnosis of 5-α-Reductase Type 2 Defciency in an Adolescent Girl with Primary Amenorrhoea Case report

Authors: Abdul-Rahman A. Hummadi| Department of Endocrinology & Internal Medicine, King Fahad Central Hospital, Jizan, Saudi Arabia, Ayel O. Yahya| Department...
( 20 downloads)
Abstract

Defciency of the 5-α-reductase enzyme has been found to affect male sexual development. We report an 18-year-old patient who was referred to an endocrinology clinic in Jizan, Saudi Arabia, in April 2014 with primary amenorrhoea, virilisation and a lack of secondary sex characteristics. As female external genitalia were present at birth, she had been raised as a female. Magnetic resonance imaging revealed no uterine or ovarian tissue in the pelvis and the presence of a scrotal sac. She was diagnosed with 5-α-reductase type 2 defciency, a 46,XY disorder of sexual development. Typically, affected males have pseudovaginal perineoscrotal hypospadias and ambiguous genitalia at birth. Individuals who have been raised as female manifest characteristics of virilisation at puberty, including deepening of the vocal tone, phallus enlargement, scrotal hyperpigmentation and increased muscle mass.

Keywords: 46, XY Disorders of Sex Development, Testosterone 5-alpha-Reductase, Dihydrotestosterone, Hypospadias, Puberty
A Case of Multiple Myeloma Presenting with Diabetes Insipidus

A Case of Multiple Myeloma Presenting with Diabetes Insipidus

Authors: Rudrajit Paul| Department of Medicine, Kolkata Medical College, Kolkata, West Bengal, India, Aditya V. Ruia| Department of Medicine, Kolkata Medical C...
( 20 downloads)
Abstract

Multiple myeloma (MM) can present with involvement of the central nervous system in the form of nerve palsy, plasma cell masses or, rarely, with endocrinological effects due to involvement of the pituitary gland. Usually, in such cases, the disease has a rapid progression and poor prognosis. We report a 52-year-old man who was admitted to the Kolkata Medical College, Kolkata, India, in 2016 with a prolonged low-grade fever and hypernatremia. Shortly afterwards, the patient began to complain of increased urinary frequency and drowsiness. Te hypernatremia was treated with intranasal desmopressin and free water replacement. Serum protein electrophoresis and an immunofxation study revealed an immunoglobulin G-κ monoclonal band. Magnetic resonance imaging of the pituitary gland revealed the absence of a posterior bright spot and spotty infltration of the pituitary fossa. A bone marrow biopsy confrmed a diagnosis of cranial diabetes insipidus due to posterior pituitary MM infltration.

Keywords: Multiple Myeloma, Diabetes Insipidus, Pituitary Gland, Hypernatremia, Case Report, India
Delayed Treatment Response in a Neonate with Multisystem Langerhans Cell Histiocytosis Case report and review of literature

Delayed Treatment Response in a Neonate with Multisystem Langerhans Cell Histiocytosis Case report and review of literature

Authors: Amitabh Singh| Departments of Pediatrics, Chacha Nehru Bal Chikitsalya, New Delhi, India, Anirban Mandal| Department of Pediatrics, Sitaram Bhartia In...
( 15 downloads)
Abstract

Langerhans cell histiocytosis (LCH) is a rare proliferative disorder of the Langerhans cells, which are part of the mononuclear phagocytic system. Te disorder varies in terms of the extent of the disease, its natural course and patient outcomes. While skin rashes are a common presentation of neonatal LCH, other systems or organs may also be involved. Delays in the diagnosis of neonatal LCH may occur due to its non-specifc presentation and a lack of awareness of the condition among doctors. We report a two-month-old male neonate who presented to the Chacha Nehru Bal Chikitsalya hospital, New Delhi, India, in 2016 after the onset of pulmonary symptoms. He had been noted to have a generalised rash which had progressively worsened from 15 days of age. Following a skin biopsy and chest imaging, he was diagnosed with multisystem LCH with risk organ involvement. Tere was a delayed response to combined chemotherapy with no major side-effects.

Keywords: Langerhans Cell Histiocytosis, Seborrheic Dermatitis, Tachypnea, Anemia, Infant, Case Report
Struma Ovarii with Pseudo-Meigs’ Syndrome and Raised Cancer Antigen-125 Levels Masquerading as an Ovarian Carcinoma Case report and literature review

Struma Ovarii with Pseudo-Meigs’ Syndrome and Raised Cancer Antigen-125 Levels Masquerading as an Ovarian Carcinoma Case report and literature review

Authors: Surekha Yadav| Department of Pathology, Maulana Azad Medical College, New Delhi, India, Reena Tomar| Department of Pathology, Maulana Azad Medical Col...
( 19 downloads)
Abstract

Te monodermal teratoma struma ovarii is a rare ovarian tumour; however, struma ovarii presenting with pseudo-Meigs’ syndrome and raised cancer antigen (CA)-125 levels is even rarer. In elderly patients, this presentation can potentially lead to a misdiagnosis of a malignant ovarian carcinoma, resulting in unnecessary extensive surgery. We report a 55-year-old female who presented to the Lok Nayak Jai Prakash Narayan Hospital, New Delhi, India, in 2016 with progressive abdominal discomfort, fatigue and abdominal distention. Clinical and radiological features were indicative of a malignant ovarian tumour and ascites. Serum CA-125 levels were elevated at 258 U/mL. A left-sided salpingo-oophorectomy was performed, after which the serum CA-125 levels normalised. Tere was no evidence of recurrence at a six-month follow-up. A frozen section procedure confrmed the diagnosis of a struma ovarii. Tis rare condition should be considered as a differential diagnosis in patients presenting with ovarian masses, ascites and raised CA-125 levels.

Keywords: Ovarian Cancers, Struma Ovarii, Meigs’ Syndrome, Carcinoma, Ascites, Frozen Section
Solitary Peripheral Osteoma of the Hard Palate Case report and literature review

Solitary Peripheral Osteoma of the Hard Palate Case report and literature review

Authors: Fotios Bountaniotis| Department of Oral & Maxillofacial Surgery, Dental School of Athens, Athens, Greece, Ioannis Melakopoulos| Department of Oral & M...
( 22 downloads)
Abstract

Osteomas are benign slow-growing osteogenic lesions of unknown aetiology which can be central, peripheral or extraskeletal. Peripheral osteomas of the maxilla are very uncommon. We report a 72-year-old female patient who presented to the Department of Oral & Maxillofacial Surgery, Dental School of Athens, Athens, Greece, in 2015 with swelling of the palate following a tooth extraction. Clinical and radiographical features were indicative of a solitary peripheral osteoma of the hard palate. An excisional biopsy and histological examination of the lesion confrmed the diagnosis. No complications occurred during the postoperative period and there was no evidence of recurrence at a one-year follow-up.

Keywords: Bone Tissue Neoplasms, Osteomas, Maxilla, Hard Palate, Case Report, Greece
Use of Cone-Beam Computed Tomography in the Diagnosis and Treatment of an Unusual Canine Abnormality

Use of Cone-Beam Computed Tomography in the Diagnosis and Treatment of an Unusual Canine Abnormality

Authors: Archana Gopalakrishnan| Departments of Oral Medicine & Radiology, Government Dental College Kozhikode, Kozhikode, Kerala, India, Unnikrishna K.| Depar...
( 15 downloads)
Abstract

Diagnosis and treatment planning are important for successful endodontic treatment. We report a 24-year old male who presented to the Government Dental College in Kozhikode, Kerala, India, in 2015 with pain in his right upper canine. A digital periapical radiograph indicated the presence of a supernumerary tooth superimposing the root of the canine. However, cone-beam computed tomography (CBCT) confrmed that the supernumerary tooth was an illusion and that the canine root had a sharp invagination involving the labial and pulpal dentin surfaces, with evidence of periapical bone destruction. A blunt resection was performed at the level of the invagination and the resected end was flled with a dentin substitute. At a one-year follow-up, the patient was asymptomatic and the periapical region appeared to be healing well. Tis report highlights the importance of CBCT in visualising abnormal canine morphology, thus allowing appropriate endodontic treatment.

Keywords: Diagnostic Imaging, Cone-Beam Computed Tomography, Tooth Abnormalities, Case Report, India
Group A Streptococcal Pericarditis in a Four-Month-Old Infant Case report

Group A Streptococcal Pericarditis in a Four-Month-Old Infant Case report

Authors: Badria R. Al-Waili| Departments of Pediatric Infectious Diseases, Royal Hospital, Muscat, Oman, Sunny K. Zacharias| Departments of Cardiothoracic Surg...
( 24 downloads)
Abstract

Purulent pericarditis is uncommon among paediatric patients and cases caused by group A Streptococcus (GAS) are even rarer. We report a four-month-old female infant who was referred to the Royal Hospital, Muscat, Oman, in 2015 with pericardial effusion and cardiac tamponade. She had initially presented to a secondary hospital with a two-week history of fever, a runny nose and shortness of breath. Blood and pericardial fluid cultures confrmed GAS isolates. Te infant was treated with a two-week course of antibiotics and made a complete recovery with no echocardiographical evidence of pericardial effusion at a two-month follow-up. To the best of the authors’ knowledge, this case constitutes the youngest infant to present with GAS pericarditis. As invasive GAS infections can present in infancy, early recognition and treatment is required.

Keywords: Infant, Pericarditis, Pericardial Effusion, Streptococcus Group A, Case Report, Oman

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