Sultan Qaboos University Medical Journal

Sultan Qaboos University Medical Journal

Basic info

  • Publisher: Sultan Qaboos University
  • Country of publisher: oman
  • Date added to EuroPub: 2017/Sep/12

Subject and more

  • LCC Subject Category: Biochemistry, Biomedicine, Medicine
  • Publisher's keywords: Medicine, Biomedicine, Community Health, Family Medicine, Health Sciences, Biochemistry
  • Language of fulltext: english
  • Full-text formats available: PDF

Publication charges

  • Article Processing Charges (APCs): No
  • Submission charges: No
  • Waiver policy for charges? No

Editorial information

Open access & licensing

  • Type of License: CC BY
  • License terms
  • Open Access Statement: Yes
  • Year open access content began: 1999
  • Does the author retain unrestricted copyright? False
  • Does the author retain publishing rights? False

Best practice polices

  • Permanent article identifier: DOI
  • Content digitally archived in: LOCKSS
  • Deposit policy registered in: None

This journal has '1136' articles

Transposition of the Great Arteries and Coarctation of the Aorta in an Infant Presenting with Bronchiolitis An incidental fnding

Transposition of the Great Arteries and Coarctation of the Aorta in an Infant Presenting with Bronchiolitis An incidental fnding

Authors: Khaloud S. Al-Mukhaini| Departments of Child Health, Royal Hospital, Muscat, Oman, Ala M. Mohamed| Departments of Pediatric Cardiology, Royal Hospital...
( 19 downloads)
Abstract

Te transposition of the great arteries (TGA) is a complex congenital heart disease which usually presents as cyanosis in neonates with limited mixing between the systemic and pulmonary circulatory systems. A delayed diagnosis of TGA can lead to ventricular failure. We report a six-week-old infant who was admitted to the paediatric Intensive Care Unit of the Royal Hospital, Muscat, Oman, in 2016 for bronchiolitis. During admission, she was incidentally diagnosed with TGA and coarctation of the aorta. Postnatal screening, including the use of pulse oximetry, plays a signifcant role in avoiding a late diagnosis of TGA; however, this screening tool is not widely used in Oman. Moreover, the common practice of applying a pulse oximetry probe only to the foot may have been limited in the current case due to the reverse differential saturation between the upper and lower limbs caused by this particular combination of lesions.

Keywords: Transposition of Great Arteries, Cyanosis, Neonatal Screening, Pulse Oximetry, Case Report, Oman
Anomalous Origin of the Right Coronary Artery from the Left Coronary Sinus Case report

Anomalous Origin of the Right Coronary Artery from the Left Coronary Sinus Case report

Authors: Ziyab K. Sarfaraz| General Surgery Residency Programme, Oman Medical Speciality Board, Muscat, Oman, Mohammad S. Siddiqi| Department of Surgery, Sulta...
( 19 downloads)
Abstract

Te anomalous origin of the right coronary artery from the left coronary sinus is a rare congenital disorder and can often result in sudden death upon initial presentation. We report a 19-year-old male patient who was referred to the Sultan Qaboos University Hospital, Muscat, Oman, in 2015 with multiple episodes of exertional angina. He was diagnosed as having an anomalous right coronary artery arising from the left coronary sinus following an intraoperative transesophageal echocardiogram. An unroofng ostioplasty of the anomalous right coronary artery was successful. Details of the surgical management of this anomaly are discussed.

Keywords: Congenital Abnormalities, Coronary Artery, Coronary Sinus, Anatomic Variation, Myocardial Ischemia, Case Report
Segmental Spinal Muscular Atrophy Localised to the Lower Limbs First case from Oman

Segmental Spinal Muscular Atrophy Localised to the Lower Limbs First case from Oman

Authors: Roshan Koul| Departments of Child Health, Sultan Qaboos University Hospital, Muscat, Oman, Amna Al-Futaisi| Departments of Child Health, Sultan Qaboos...
( 22 downloads)
Abstract

Spinal muscular atrophy (SMA) is a genetic lower motor neuron disease. It usually involves all of the skeletal muscles innervated by the anterior horn cells of the spinal cord. In rare cases, there is also localised involvement of the spinal cord. We report a 10-year-old boy who presented to the Sultan Qaboos University Hospital, Muscat, Oman, in 2015 with muscle weakness restricted to the lower limbs. Te presence of a homozygous deletion within the survival of motor neuron 1 gene confrmed the diagnosis of SMA. To the best of the authors’ knowledge, this is the frst report of an Omani patient with segmental SMA involving only the lower limbs. Treatment for this rare and relatively benign form of SMA is symptomatic and includes physiotherapy.

Keywords: Spinal Muscular Atrophies of Childhood, Spinal Muscular Atrophy, Segmental, Muscle Weakness, Pes Cavus, Case Report
Bacille Calmette-Guérin Vaccine-Induced Tuberculous Hip Osteomyelitis in an Infant Case report

Bacille Calmette-Guérin Vaccine-Induced Tuberculous Hip Osteomyelitis in an Infant Case report

Authors: Mohammed S. Al-Azri| College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman, Jazel Manarang| Department of Child Health, Royal...
( 16 downloads)
Abstract

To this day, tuberculosis (TB) continues to pose a signifcant global health burden. Te World Health Organization’s Expanded Programme on Immunization (EPI) recommends the bacille Calmette-Guérin (BCG) vaccine for infants to protect against the haematogenous spread of primary TB and other more severe types of TB infection. We report an eight-month-old boy who presented to the Armed Forces Hospital, Muscat, Oman, in 2015 with a one-month history of intermittent fever associated with a limited range of motion in the right hip area. He was up-to-date with his EPI vaccinations and had no history of exposure to individuals with TB infections. He was initially treated for bacterial septic arthritis; however, a GeneXpert TB assay revealed the presence of Mycobacterium tuberculosis, BCG strain. To the best of the authors’ knowledge, this is the frst documented case from Oman of a child with TB hip osteomyelitis due to a BCG vaccination.

Keywords: Tuberculosis, BCG Vaccine, Vaccination, adverse effects, Osteomyelitis, Case Report
Umbilical Endometriosis

Umbilical Endometriosis

Authors: Ayida A. Al-Khalili| Departmemt of Family Medicine & Public Health, Sultan Qaboos University Hospital, Muscat, Oman, Department of Dermatology & Skin...
( 19 downloads)
Abstract



Keywords: null
Deciphering the Role of the Barr Body in Malignancy An insight into head and neck cancer

Deciphering the Role of the Barr Body in Malignancy An insight into head and neck cancer

Authors: Deepti Sharma| Department of Oral & Maxillofacial Pathology, Christian Dental College, Ludhiana, Punjab, India, George Koshy| Department of Oral & Max...
( 23 downloads)
Abstract

X chromosome inactivation is the epitome of epigenetic regulation and long non-coding ribonucleic acid function. Te differentiation status of cells has been ascribed to X chromosome activity, with two active X chromosomes generally only observed in undifferentiated or poorly differentiated cells. Recently, several studies have indicated that the reactivation of an inactive X chromosome or X chromosome multiplication correlates with the development of malignancy; however, this concept is still controversial. Tis review sought to shed light on the role of the X chromosome in cancer development. In particular, there is a need for further exploration of the expression patterns of X-linked genes in cancer cells, especially those in head and neck squamous cell carcinoma (HNSCC), in order to identify different prognostic subpopulations with distinct clinical implications. Tis article proposes a functional relationship between the loss of the Barr body and the disproportional expression of X-linked genes in HNSCC development.

Keywords: Sex Chromatin, X Chromosome, Lyonization, X-Linked Genes, Cell Differentiation, Cancer
Troponin Testing in the Emergency Department Real world experience

Troponin Testing in the Emergency Department Real world experience

Authors: Mohammed Al-Maskari| Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman, Mahmoud Al-Makhdami| Department of Medicine, Sultan Qabo...
( 17 downloads)
Abstract

Objectives: Te aim of this study was to examine patterns of troponin testing in the emergency department of a large tertiary care hospital in Oman and to determine its effect on patient management, including length of hospital stay (LOS). Methods: Tis retrospective study analysed the medical records of all adult patients undergoing troponin testing in the emergency department of the Sultan Qaboos University Hospital, Muscat, Oman, during the month of July 2015. Patients who presented with an ST-elevation myocardial infarction were excluded. Results: A total of 4,845 patients attended the emergency department during the study period; of these, troponin tests were ordered for 588 patients. Te majority of the patients had negative troponin test results (81.3%). Chest pain, palpitations and breathlessness were the most common presenting complaints for those with positive troponin results. However, 41.8% of patients did not have any cardiac symptoms. Individuals with positive troponin tests had a signifcantly longer LOS compared to those with negative tests (mean: three versus one day; P = 0.001). In total, only 28.2% of those with positive troponin test results had fnal diagnoses associated with a cardiac condition, such as heart failure, an acute coronary syndrome (ACS), atrial fbrillation or other types of arrhythmia. Conclusion: A positive troponin test was associated with increased LOS; however, only a small proportion of these patients had a fnal diagnosis associated with a cardiac condition. Guidelines should be provided to ensure that troponin testing is performed only in cases where an ACS is suspected.

Keywords: Emergency Department, Troponin, Cardiovascular Abnormality, Acute Coronary Syndrome, Length of Stay, Oman
Epidemiology of Chronic Hepatitis C Infections at a Tertiary Care Centre in Oman

Epidemiology of Chronic Hepatitis C Infections at a Tertiary Care Centre in Oman

Authors: Said A. Al-Busaf| Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman, Halima Al-Shuaili| Internal M...
( 17 downloads)
Abstract

Objectives: Chronic hepatitis C (CHC) is a leading cause of liver cirrhosis and hepatocellular carcinoma (HCC) worldwide. However, there is a lack of data regarding the epidemiology of CHC in Oman. Tis study aimed to describe the clinicopathological characteristics and outcomes of CHC-infected patients at a tertiary care hospital in Oman. Methods: Tis retrospective descriptive hospital-based study included all CHC-infected patients who presented to the Sultan Qaboos University Hospital (SQUH) in Muscat, Oman, between January 2010 and December 2015. Te baseline demographic, clinical, laboratory and radiological data of the patients were analysed. Results: A total of 603 CHC-infected patients were identifed during the study period; of these, 65.8% were male and the mean age was 44.8 ± 16.5 years. Te main risk factors associated with CHC infection were intravenous drug abuse (23.9%) and a history of blood transfusions (20.7%). Te most prevalent virus genotypes were 1 and 3 (44.0% and 35.1%, respectively). Upon initial presentation, 33.0% of the cohort had liver cirrhosis; of these, 48.7% had decompensated cirrhosis and 23.1% had HCCs. Liver transplantation was only performed for 7.5% of the cirrhosis patients, mostly as a curative treatment for HCC. Conclusion: Te implementation of national policies to prevent hepatitis C transmission and encourage the early screening of at-risk patients is recommended to reduce the burden and consequences of this disease in Oman.

Keywords: Chronic Hepatitis C, Hepatocellular Carcinoma, Liver Cirrhosis, Infectious Disease Transmission, Genotypes, Oman

About Europub

EuroPub is a comprehensive, multipurpose database covering scholarly literature, with indexed records from active, authoritative journals, and indexes articles from journals all over the world. The result is an exhaustive database that assists research in every field. Easy access to a vast database at one place, reduces searching and data reviewing time considerably and helps authors in preparing new articles to a great extent. EuroPub aims at increasing the visibility of open access scholarly journals, thereby promoting their increased usage and impact.