Sultan Qaboos University Medical Journal

Sultan Qaboos University Medical Journal

Basic info

  • Publisher: Sultan Qaboos University
  • Country of publisher: oman
  • Date added to EuroPub: 2017/Sep/12

Subject and more

  • LCC Subject Category: Biochemistry, Biomedicine, Medicine
  • Publisher's keywords: Medicine, Biomedicine, Community Health, Family Medicine, Health Sciences, Biochemistry
  • Language of fulltext: english
  • Full-text formats available: PDF

Publication charges

  • Article Processing Charges (APCs): No
  • Submission charges: No
  • Waiver policy for charges? No

Editorial information

Open access & licensing

  • Type of License: CC BY
  • License terms
  • Open Access Statement: Yes
  • Year open access content began: 1999
  • Does the author retain unrestricted copyright? False
  • Does the author retain publishing rights? False

Best practice polices

  • Permanent article identifier: DOI
  • Content digitally archived in: LOCKSS
  • Deposit policy registered in: None

This journal has '1136' articles

The Role of N-Acetylcysteine Supplementation on the Oxidative Stress Levels, Genotoxicity and Lineage Commitment Potential of Ex Vivo Murine Haematopoietic Stem/Progenitor Cells

The Role of N-Acetylcysteine Supplementation on the Oxidative Stress Levels, Genotoxicity and Lineage Commitment Potential of Ex Vivo Murine Haematopoietic Stem/Progenitor Cells

Authors: Zariyantey A. Hamid, Hui Y. Tan, Paik W. Chow, Khairul A. W. Harto, Chin Y. Chan, Jamaludin Mohamed
( 8 downloads)
Abstract

Objectives: Te ex vivo maintenance of haematopoietic stem/progenitor cells (HSPCs) is crucial to ensure a sufcient supply of functional cells for research or therapeutic applications. However, when exposed to reactive oxygen species (ROS) in a normoxic microenvironment, HSPCs exhibit genomic instability which may diminish their quantity and quality. Tis study aimed to investigate the role of N-acetylcysteine (NAC) supplementation on the oxidative stress levels, genotoxicity and lineage commitment potential of murine haematopoietic stem/progenitor cells (HSPCs). Methods: Tis study was carried out at the Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia, between June 2016 and July 2017. Bone marrow cells were isolated from nine mice and cultured in a growth medium. Various concentrations of NAC between 0.125–2 µM were added to the culture for 48 hours; these cells were then compared to non-supplemented cells harvested from the remaining three mice as the control group. A trypan blue exclusion test was performed to determine cell viability, while intracellular ROS levels and genotoxicity were determined by hydroethidine staining and comet assay, respectively. Te lineage commitment potential of erythroid, myeloid and pre-B-lymphoid progenitor cells was evaluated via colony-forming cell assay. Results: NAC supplementation at 0.25, 0.5 and 2 µM signifcantly increased cell viability (P <0.050), while intracellular ROS levels signifcantly decreased at 0.25 and 0.5 µM (P <0.050). Moreover, DNA damage was signifcantly reduced at all NAC concentrations (P <0.050). Finally, the potential lineage commitment of the cells was not signifcantly affected by NAC supplementation (P >0.050). Conclusion: Te fndings of this study indicate that NAC supplementation may potentially overcome the therapeutic limitations of ex vivo-maintained HSPCs.

Keywords: Hematopoietic Stem Cells; N-acetylcysteine; Reactive Oxygen Species; DNA Damage; Cell Lineage
Asthma Clinics in Primary Healthcare Centres in Oman Do they make a difference?

Asthma Clinics in Primary Healthcare Centres in Oman Do they make a difference?

Authors: Abdulaziz Al-Mahrezi, Sawsan Baddar, Sheikha Al-Siyabi, Safaa Al-Kindi, Ibrahim Al-Zakwani, Omar Al-Rawas
( 11 downloads)
Abstract

Objectives: Tis study aimed to determine the effect of newly established asthma clinics (ACs) on asthma management at primary healthcare centres (PHCs) in Oman. Methods: Tis retrospective crosssectional study was conducted between June 2011 and May 2012 in seven PHCs in the Seeb wilayat of Muscat, Oman. All ≥6-year-old asthmatic patients visiting these PHCs during the study period were included. Electronic medical records were reviewed to determine which clinical assessment and management components had been documented. Results: A total of 452 asthmatic patients were included in the study. Te mean age was 35 ± 21 years old (range: 6–95 years) and the majority (57%) were female. In total, 288 (64%) cases were managed at ACs and 164 (36%) were managed at general clinics (GCs). Signifcant differences were noted in the documentation of cases managed at ACs compared to those at GCs, including history-taking information regarding signs and symptoms (91% versus 19%; P <0.001), trigger factors (79% versus 16%; P <0.001) and a history of atopy (81% versus 17%; P <0.001), smoking (61% versus 7%; P <0.001), asthma exacerbations (73% versus 10%; P <0.001) or previous admissions (63% versus 10%; P <0.001). Furthermore, prescription rates of inhaled corticosteroids (72% versus 61%; P = 0.021) and short-acting β-agonists (93% versus 82%; P = 0.001) were signifcantly higher at ACs compared to GCs. Conclusion: Overall, the fndings indicated that ACs have had a positive impact on asthma management at the studied PHCs.

Keywords: Asthma; Disease Management; Patient Compliance; Medical History Taking; Medical Records; Documentation; Oman
Daytime Sleepiness Among Young Adult Omani Car Drivers

Daytime Sleepiness Among Young Adult Omani Car Drivers

Authors: Mohammed A. Al-Abri, Samir Al-Adawi, Ibrahim Al-Abri, Faisal Al-Abri, Atsu Dorvlo, Ronald Wesonga, Sanjay Jaju
( 13 downloads)
Abstract

Objectives: Sleepiness and fatigue play signifcant roles in exacerbating the occurrence of car crashes. However, there is a dearth of studies examining the prevalence of sleepiness while driving among Omanis. Tis study aimed to determine the proportion of young Omani adults who confess to daytime sleepiness while driving and to investigate associations between gender, daytime sleepiness and risk of obstructive sleep apnoea syndrome (OSAS). Methods: Tis cross-sectional study took place at the Sultan Qaboos University Hospital, Muscat, Oman, between May and July 2014 and included 600 young adult Omani non-commercial drivers. Te Berlin Questionnaire and Epworth Sleepiness Scale (ESS) were distributed among the participants, along with additional questions about their sleeping habits. Associations between daytime sleepiness while driving and nocturnal sleep duration, risk of OSAS and gender were determined. Results: A total of 492 private vehicle drivers took part in the study (response rate: 82%), of which 50.4% were male. Overall, 124 Omanis (25.2%) reported experiencing daytime sleepiness while driving at least once per month. Tere was a signifcant association between nocturnal sleep duration of <6 hours and sleepiness while driving (P = 0.042). Female participants were signifcantly more likely to score >10 on the ESS, indicating a greater propensity for daytime sleepiness (P = 0.006). However, male drivers were signifcantly more likely to report sleepiness while driving (P = 0.001). Conclusion: Sleepiness while driving was common among young male drivers in Oman and might be due to nocturnal sleep deprivation. Further studies are needed so that preventative measures can be developed.

Keywords: Motor Vehicles; Trafc Accidents; Sleep; Fatigue; Obstructive Sleep Apnea Syndrome; Oman
Evaluation of Mitotic Figures and Cellular and Nuclear Morphometry of Various Histopathological Grades of Oral Squamous Cell Carcinoma Comparative study using crystal violet and Feulgen stains

Evaluation of Mitotic Figures and Cellular and Nuclear Morphometry of Various Histopathological Grades of Oral Squamous Cell Carcinoma Comparative study using crystal violet and Feulgen stains

Authors: Kashmira Kesarkar, Avinash Tamgadge, Treville Peirera, Sandhya Tamgadge, Swati Gotmare, Pooja Kamat
( 11 downloads)
Abstract

Objectives: Te objectives of this study were to quantitatively estimate the number of mitotic fgures (MFs) and evaluate the cellular and nuclear features of various histological grades of oral squamous cell carcinoma (OSCC) using Feulgen and 1% crystal violet stains. Methods: Tis case-control study took place at the Dr D. Y. Patil Dental College & Hospital in Mumbai, Maharashtra, India, between June and December 2016. A total of 51 samples were retrieved from the hospital archives. Of these, 15 well-differentiated, 15 moderately-differentiated and six poorly-differentiated OSCC samples formed the case group while 15 samples of normal gingival mucosa constituted the control group. Each sample was dyed using Feulgen and 1% crystal violet stains and the mitotic count, nuclear area (NA), cellular area (CA), nuclear perimeter (NP), cellular perimeter (CP) and nuclear-to-cytoplasmic (N/C) ratio was calculated using computeraided morphometry techniques. Results: Te number of MFs visible per feld was signifcantly higher in Feulgen-stained sections as compared to those stained with crystal violet (P = 0.050). In addition, the NA, NP, CA and CP values and N/C ratios of samples in the experimental group increased signifcantly in accordance with an increase in OSCC grade (P <0.001). Conclusion: Te Feulgen stain is more reliable than 1% crystal violet in terms of the selective staining of MFs. Moreover, the fndings of this study indicate that computer-based morphometric analysis is an effective tool for differentiating between various grades of OSCC.

Keywords: Crystal Violet; Feulgen Stain; Mitotic Index; Image Cytometry; Squamous Cell Carcinoma; Oral Cancers
Epidemiology, Outcomes and Coronary Angiography Findings of Patients Following Out-of-Hospital Cardiac Arrest A single-centre experience from Oman

Epidemiology, Outcomes and Coronary Angiography Findings of Patients Following Out-of-Hospital Cardiac Arrest A single-centre experience from Oman

Authors: Sunil K. Nadar, Mohammed Mujtaba, Hafidh Al-Hadi, Muhammed Sadiq, Adil Al-Riyami, Mehar Ali, Hatim Al-Lawati
( 8 downloads)
Abstract

Objectives: Out-of-hospital cardiac arrests (OHCAs) are a leading cause of death worldwide. However, data regarding the management and outcomes of affected patients are lacking in the Middle East. Te current study aimed to present the angiographic fndings and outcomes of patients presenting with OHCA in Muscat, Oman. Methods: Tis retrospective study took place between January 2012 and December 2016 at the Sultan Qaboos University Hospital (SQUH), Muscat, Oman. All adult patients who presented following an OHCA to the Emergency Department of SQUH during the study period were included. Demographic and clinical data were collected from electronic medical records. Results: A total of 216 patients were included in the study. Te majority (63.9%) presented after having collapsed, while 22.3% presented with chest pains. Asystole was the most frequent initial cardiac rhythm (62.5%), with only 10% having ventricular tachycardia/fbrillation. Very few patients (1.4%) had received cardiopulmonary resuscitation (CPR) prior to presentation. In total, 85 patients (39.4%) returned to spontaneous circulation (RSC); of these, post-RSC electrocardiography revealed an ST-segment elevation in 41.2% and normal fndings in 23.5%. Tere were 63 patients who underwent coronary angiography, with 28 requiring stenting. Overall, 13% of patients survived and were discharged, although three survivors suffered permanent hypoxic brain damage. Conclusion: Te overall survival rate of patients who had experienced an OHCA was low. Education programmes should focus on the benefts of immediate CPR for individuals experiencing an OHCA, with more opportunities for CPR training to be made available to the general public in Oman.

Keywords: Out-of-Hospital Cardiac Arrest; Cardiopulmonary Resuscitation; Patient Outcome Assessment; Survival Rate; Coronary Angiography; Oman
Attitudes of Non-Asthmatic Children Towards Their Asthmatic Peers Influence of interactions with asthmatic relatives and peers

Attitudes of Non-Asthmatic Children Towards Their Asthmatic Peers Influence of interactions with asthmatic relatives and peers

Authors: Mohammad Al-Motlaq, Nihaya Al-Sheyab
( 14 downloads)
Abstract

Objectives: Tis study aimed to examine non-asthmatic children’s acceptance of and attitudes towards their asthmatic peers in Jordan. Methods: Tis descriptive cross-sectional study was conducted between September 2015 and January 2016 among 1,812 non-asthmatic children aged 9–13 years old at 10 schools in Zarqa, Jordan. Arabic versions of the Peers Attitude Towards Children with Asthma scale and the Asthma Knowledge Test for Children were used to assess attitudes towards children with asthma and asthma-related knowledge, respectively. Results: A total of 1,586 children participated in the study (response rate: 87.5%). Of these, 158 (10%) and 399 (25.2%) children reported a family history of asthma or knew at least one person with asthma, respectively. Although 50.3% stated that they would sit next to such children in the classroom, only 34.9% reported that they would be friends with an asthmatic child. However, 73.1% of the non-asthmatic children believed that asthmatic children were not pretending to be ill and 61.4% believed that such children were not ill due to their own carelessness. Female non-asthmatic children (P <0.001), those with a family history of asthma (P = 0.004) and those who knew other individuals with asthma (P <0.001) had signifcantly more positive attitudes towards and acceptance of their asthmatic peers. In addition, age was signifcantly related to attitude scores (P <0.001). However, there was no correlation between asthma-related knowledge and the children’s attitudes towards peers with asthma (P = 0.611). Conclusion: Previous interactions with asthmatic family members or peers were found to signifcantly influence non-asthmatic children’s attitudes towards their asthmatic peers.

Keywords: Asthma; Children; Attitudes; Knowledge; Jordan
Arabic Translation, Validation and Cultural Adaptation of the 7-Item Hamilton Depression Rating Scale in Two Community Samples

Arabic Translation, Validation and Cultural Adaptation of the 7-Item Hamilton Depression Rating Scale in Two Community Samples

Authors: Ahmad N. Alhadi, Mohammed A. Alarabi, Abdulaziz T. Alshomrani, Raafat M. Shuqdar, Mohammad T. Alsuwaidan, Roger S. McIntyre
( 11 downloads)
Abstract

Objectives: Depression is a common mental disorder, the severity of which is frequently assessed via interview-based clinical scales such as the 7-item Hamilton Depression Rating Scale (HAMD-7). Te current study aimed to translate and examine the validity of an Arabic version of the HAMD-7 scale. Methods: Tis study took place between February and March 2016 in the Psychiatry Department of King Saud University, Riyadh, Saudi Arabia. Te HAMD-7 scale was translated into Arabic using forward and backward translation methods. A total of 153 Arabic speakers were recruited to test the translated scale, including 57 medical students and 96 members of the general public. Te Arabic version of the HAMD-7 scale was completed by trained investigators during face-toface interviews with the participants. In order to assess convergent validity, participants also completed an Arabic version of the self-assessed Patient Health Questionnaire-9 (PHQ-9) scale. Subsequently, the test-retest reliability of the translated HAMD-7 scale was evaluated two weeks later during a second interview. Results: Overall, HAMD- 7 scores were positively correlated with PHQ-9 scores (r = 0.633–0.749). Moreover, the translated HAMD-7 scale proved to be reliable in terms of test-retest reliability (intra-class correlation coefcient: 0.807; P <0.001). With regards to internal consistency, the Cronbach’s α values ranged between 0.607–0.756. Conclusion: Te Arabic HAMD-7 scale was found to be reliable and valid among two samples of Arabic speakers in Saudi Arabia. However, further research among Arab-speaking patients diagnosed with depression is needed in order to establish its usefulness in assessing the severity of depressive symptoms.

Keywords: Psychiatry; Depression; Psychometrics; Validity and Reliability; Translation; Questionnaire Design; Saudi Arabia
The Dundee Ready Education Environment Measure A prospective comparative study of undergraduate medical students’ and interns’ perceptions in Oman

The Dundee Ready Education Environment Measure A prospective comparative study of undergraduate medical students’ and interns’ perceptions in Oman

Authors: Gowda P. Prashanth, Salim K. Ismail
( 8 downloads)
Abstract

Objectives: Tis study aimed to assess perceptions of the educational environment in Oman among medical undergraduate students and interns using the Dundee Ready Education Environment Measure (DREEM) tool. Methods: Tis cross-sectional study was conducted between October 2016 and April 2017 at the Oman Medical College (OMC), Sohar, Oman. A total of 737 medical undergraduate students and interns from the OMC and College of Medicine & Health Sciences of Sultan Qaboos University in Muscat, Oman, were invited to complete the DREEM questionnaire in the form of an online survey. Mean overall scores, subscale scores and individual item scores were subsequently compared between undergraduate students and interns. Results: A total of 418 undergraduate students and interns completed the survey (response rate: 56.7%). Te mean overall DREEM score was 130.75 ± 12.69. While interns had higher mean DREEM scores than undergraduate students, this difference was not signifcant (133.00 ± 17.64 versus 128.50 ± 15.53; P = 0.326). Te mean score percentages for the perceptions of learning (66.7% versus 58.3%; P = 0.028) and perceptions of teachers (75% versus 68.2%; P = 0.038) subscales were signifcantly higher among OMC interns compared to undergraduate students from the same college. Te perceptions of the environment subscale received the lowest mean score percentages among undergraduate students and interns from both colleges. Conclusion: Overall, medical undergraduate students and interns viewed the educational environment in Oman in a positive light. It is possible that undergraduate students’ perceptions of the educational environment may become more favourable as they progress with their medical career and become interns.

Keywords: Medical Education; Undergraduate Medical Students; Internships; Perceptions; Oman
Cephalometric Norms in an Omani Adult Population of Arab Descent

Cephalometric Norms in an Omani Adult Population of Arab Descent

Authors: Prashantha S. Govinakovi, Ibrahim Al-Busaidi, Viswapurna Senguttuvan
( 8 downloads)
Abstract

Objectives: Tis study aimed to establish cephalometric norms for an Omani population of Arab descent and to compare these with established cephalometric values for Caucasians. Methods: Tis cross-sectional study was conducted at the Military Dental Centre and Oman Dental College in Muscat, Oman, between May 2014 and October 2016. A total of 150 Omani patients between 20–29 years old seeking orthodontic treatment were included. All participants had a symmetrical face, class I molar and canine relationships, proper intercuspation, a normal overjet/overbite (<3 mm) and mild spacing/crowding of the teeth (≤3 mm). Lateral cephalography was performed in centric occlusion with the lips relaxed and the head in a natural position. Cephalometric measurements were then compared with Eastman Standard norms. Results: Te Omani subjects were found to have a slightly retrusive maxilla, an increased angle between the maxillary and mandibular planes and shorter facial heights in comparison to the Eastman Standard norms. Furthermore, incisor relations were edge-to-edge in nature and the interincisal angle was reduced, suggesting that the Omani subjects had more proclined incisors. In addition, the lips were more protrusive and the nasolabial angle was more obtuse. Conclusion: In the Omani sample, increased proclination of the incisors was observed in comparison to Eastman Standard norms. As such, slightly more proclined incisors should be considered acceptable and natural among Omani patients of Arab descent. Te cephalometric fndings of this study may be helpful in the diagnosis and treatment planning of orthodontic problems among Omanis of Arab descent.

Keywords: Cephalometry, standards; Population Characteristics; Ethnic Groups; Arabs; Orthodontics; Oman
Characteristics of Critically-Ill Patients at Two Tertiary Care Hospitals in Sudan

Characteristics of Critically-Ill Patients at Two Tertiary Care Hospitals in Sudan

Authors: Hagir Sulieman, Wael El-Mahdi, Mohannad Awadelkareem, Lama Nazer
( 8 downloads)
Abstract

Objectives: Knowledge of intensive care unit (ICU) admission patterns and characteristics is necessary for the development of critical care services, particularly in low-resource settings. Tis study aimed to describe the characteristics of critically-ill patients admitted to ICUs in Sudan. Methods: Tis prospective observational study was conducted between February and May 2017 in the ICUs of two government tertiary care hospitals in Khartoum, Sudan. A total of 100 consecutive adult patients admitted to the ICUs were included in the study. Te patients’ demographic and clinical characteristics and Acute Physiologic Assessment and Chronic Health Evaluation (APACHE II) scores upon admission were recorded, as well as the reason for admission, presence of any underlying comorbidities, interventional requirements like mechanical ventilation or haemodialysis, length of stay in the ICU and patient outcome. Results: Of the sample, 58% were female and 42% were male. Te mean age was 47.4 ± 18.3 years old. Upon admission, the mean APACHE II score was 14.2 ± 9.6. In total, 54% of the patients had no known underlying comorbidities. Te most common reasons for ICU admission were neurological diseases (27%), sepsis or infectious diseases (19%) and postoperative management (12%). Mechanical ventilation and haemodialysis were required by 35% and 11% of the patients, respectively. Te average length of stay was 10.0 ± 7.2 days and the mortality rate was 24%. Conclusion: Most of the patients admitted to the ICUs were middle-aged females with no known underlying comorbidities. Larger studies are necessary to provide a comprehensive understanding of the critical care needs of Sudanese hospitals.

Keywords: Care Units; Patient Admission, trends; Critical Care Outcomes; Developing Countries; Sudan
Perceptions of Plagiarism Among Medical and Nursing Students in Erbil, Iraq

Perceptions of Plagiarism Among Medical and Nursing Students in Erbil, Iraq

Authors: Kameran H. Ismail
( 8 downloads)
Abstract

Objectives: Te rapidly rising incidence of plagiarism among students at universities throughout the world requires attention. Tis study aimed to determine the extent to which medical and nursing students in Erbil, Iraq, plagiarise, their knowledge, understanding and perceptions of plagiarism and the underlying factors that may lead them to plagiarise. Methods: Tis cross-sectional study was carried out between January and June 2017 among a sample of 400 undergraduate medical and nursing students at Hawler Medical University in Erbil. Plagiarism-related data were collected through a specially designed self-administered questionnaire. Results: In total, 280 (70%) medical students and 120 (30%) nursing students were included in the study. Te reported prevalence of plagiarism was 54.3%, with a slightly higher prevalence among male students compared to female students (54.9% versus 53.8%; P = 0.820) and medical students compared to nursing students (58.9% versus 43.3%; (P = 0.004). Alarmingly, 34.8% of the students did not know what plagiarism was, and only 28% were aware of the legal consequences of plagiarism. Reported reasons for plagiarising included laziness and the ease with which others’ work could be plagiarised, confusion, cultural reasons and pressure to meet deadlines. Conclusion: Tere was a lack of understanding of plagiarism and its legal ramifcations among undergraduate medical and nursing students in Erbil. Te fndings of this study indicate that there is an urgent need to increase students’ understanding of plagiarism and its consequences so as to reduce the incidence of this type of academic misconduct.

Keywords: Undergraduate Medical Education; Plagiarism; Medical Students; Nursing Students; Perceptions; Iraq
“Different Strokes” A management dilemma

“Different Strokes” A management dilemma

Authors: Arunodaya R. Gujjar, Mortada El-Tigani, Darshan Lal, Anupam K. Kakaria, Abdullah R. Al-Asmi
( 9 downloads)
Abstract

Stroke is a common medical emergency resulting from numerous pathophysiological mechanisms and with varied clinical manifestations; as such, the diagnosis of stroke requires diligent clinical assessment. When different stroke syndromes occur in the same patient, it may cause a dilemma in terms of diagnosis and management. Tis continuing medical education article describes an interesting patient with recurrent neurological events, highlighting the complex pathophysiological processes associated with cerebrovascular syndromes. It offers readers the opportunity to apply their own basic neuroscience knowledge and clinical skills to solve the challenges encountered during the course of diagnosing and treating this patient. Specifcally, the article aims to familiarise readers with an approach to diagnosing brainstem strokes and the diverse manifestations of a common stroke syndrome.

Keywords: Stroke; Lacunar Stroke; Cerebral Hemorrhage; Cerebral Small Vessel Disease; Continuing Medical Education
Paliperidone Palmitate-Induced Delirium in an Adolescent with Schizophrenia Case report

Paliperidone Palmitate-Induced Delirium in an Adolescent with Schizophrenia Case report

Authors: Hassan Mirza, Duncan Harding, Naser Al-Balushi
( 10 downloads)
Abstract

Schizophrenia is a serious long-term mental disorder which usually presents in adolescence or early adulthood. However, poor adherence to oral antipsychotics can lead to relapse and rehospitalisation. We report an adolescent male with schizophrenia who was referred to the South London & Maudsley National Health Service Foundation Trust, London, UK, in 2015 due to worsening psychotic symptoms. Following poor compliance with oral medications, a four-week regimen of paliperidone palmitate long-acting injections was initiated, with an initial positive response. However, 10 days after the second dose, the patient developed severe acute-onset delirium with fluctuating levels of consciousness. Paliperidone palmitate was discontinued and the patient instead underwent a course of zuclopenthixol decanoate long-acting injections with a favourable outcome.

Keywords: Adolescent Psychiatry; Schizophrenia; Antipsychotic Agents; Delirium; Paliperidone Palmitate; Zuclopenthixol; Case Report; United Kingdom
Nasopharyngeal Salivary Gland Anlage Tumour A rare cause of neonatal respiratory distress

Nasopharyngeal Salivary Gland Anlage Tumour A rare cause of neonatal respiratory distress

Authors: Salma M. Al-Sheibani, Kiran P. Sawardekar, Salwa J. Habib, Hunaina M. Al-Kindi
( 8 downloads)
Abstract

A salivary gland anlage tumour (SGAT) is a very rare type of benign tumour that usually presents in early infancy with respiratory distress which is exacerbated upon feeding. We report a full-term male neonate who was referred to the Al Nahdha Hospital, Muscat, Oman, in 2015 with severe neonatal respiratory distress due to a nasopharyngeal obstruction immediately after birth. Computed tomography and magnetic resonance imaging revealed a well-circumscribed mass in the nasopharynx, without intracranial extension. Histopathological analysis of the lesion confrmed a diagnosis of SGAT. Following excision of the tumour, the postoperative period was uneventful. No recurrence was observed over the next two years. Tis case report highlights the importance of the early recognition of this extremely rare and potentially life-threatening, yet easily curable, condition.

Keywords: Nasopharyngeal Neoplasms; Salivary Gland Neoplasms; Neonatal Respiratory Distress Syndrome; Case Report; Oman
Inflammatory Reactions to Red Tattoo Inks Three cases highlighting an emerging problem

Inflammatory Reactions to Red Tattoo Inks Three cases highlighting an emerging problem

Authors: Ricardo Ruiz-Villaverde, Pablo Fernandez-Crehuet, Paula Aguayo-Carreras, Jose L. Hernandez-Centeno, Carlos Cuenca-Barrales
( 8 downloads)
Abstract

In recent years, tattoos have become more commonplace. However, this can result in various inflammatory processes, the management of which can be challenging in daily clinical practice. Tattoo-related inflammatory reactions can comprise different patterns, including acute and immediate reactions, foreign body granulomas, sarcoid granulomas, isomorphic lesions, allergic contact dermatitis and photosensitivity. We report three cases who were referred to the Dermatology Outpatient Clinic of the Hospital Universitario San Cecilio, Granada, Spain, in 2017 with various skin reactions in the red-ink areas of their tattoos. Screening was performed for infectious diseases like atypical mycobacterial infections and systemic processes such as sarcoidosis. A good therapeutic response was achieved in all cases. An adequate differential diagnosis is essential for the therapeutic management of this emerging health problem.

Keywords: Non-Terapeutic Body Modifcation; Tattooing, adverse effects; Inks; Foreign Body Reaction; Inflammation; Case Report; Spain

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