Journal of Herbal Drugs

Journal of Herbal Drugs

Basic info

  • Publisher: Islamic Azad University, Shahrekord Branch
  • Country of publisher: iran, islamic republic of
  • Date added to EuroPub: 2018/Feb/04

Subject and more

  • LCC Subject Category: Marketing, Agricultural Science, Biotechnology, Botany, Genetics, Plant Sciences, Medicine, Pharmacology, Toxicology
  • Publisher's keywords: Herbs, Cultivation or Agronomy, Breeding, Biotechnology, Marketing and Economy, Medicinal Plants, Genetic
  • Language of fulltext: english, persian
  • Full-text formats available: PDF

Publication charges

  • Article Processing Charges (APCs): No
  • Submission charges: No
  • Waiver policy for charges? No

Editorial information

Open access & licensing

  • Type of License: CC BY
  • License terms
  • Open Access Statement: Yes
  • Year open access content began: 2011
  • Does the author retain unrestricted copyright? False
  • Does the author retain publishing rights? False

Best practice polices

  • Permanent article identifier: DOI
  • Content digitally archived in: Nopolicy
  • Deposit policy registered in: None

This journal has '260' articles

The anti-parasite activity of garlic tablet on Limnatis nilotica

The anti-parasite activity of garlic tablet on Limnatis nilotica

Authors: Tahereh Farkhondeh; Parisa Sedighara; Ehsan Bahmani; Majid Gholami Ahangaran; Elham Moghtadaei
( 18 downloads)
Abstract

Background & Aim: Today, the use of medicinal plants has been growing because of less side effects than chemical drugs in the treatment of diseases particularly infectious diseases. According to the available scientific evidence, garlic is an effective anti-parasitic drug. In the present research will be study the inhibitory effect of garlic tablet on Limnatis nilotica. Material & Methods: To study the garlic tablet effect on paralysis and mortality of leech Leeches were placed in plastic vessels containing 600 ml of water and adding ground garlic tablet 400, 800, 1200 mg. From 1 to 4 hours after the exposure paralysis and death rate of the leeches were recorded accurately. Results & Discussion: The results indicated no effect of garlic tablet on motor response and mortality rate of the leeches. This problem probably caused by removal of thiosulfinate group of garlic tablet. Conclusion: This Study confirming the role of thiosulfinate compound to cause anti-parasitic property of garlic. Possibly, extract of garlic can be effective for leech infestation due to thiosulfinate compound.

Keywords: Antiparasite Garlic tablet Limnatis nilotica Thiosulfine
Evaluation of ecotype and chemotype diversity of Thymus daenensis Celak. on Isfahan and Chaharmahal va Bakhtiari provinces

Evaluation of ecotype and chemotype diversity of Thymus daenensis Celak. on Isfahan and Chaharmahal va Bakhtiari provinces

Authors: Abnoos Karimi; Abdollah Ghasemi Pirbalouti; Fatemeh Malekpoor; Mehdi Yousefi; Ahmad Reza Golparvar
( 18 downloads)
Abstract

Background & Aim: Thymus daenensis Celak. is one of the herbal and perennial medicinal plants belonging to Lamiaceae which grows widely in Isfahan and Chaharmahal va Bakhtiari provinces. All of its floral on aerial part has extensive use in preparing traditional medicines. The major constitutes of Thymus daenensis Celak. are thymol and carvacrol. Since ecological conditions have a great role in growth of the plant, and on the quality and amount of effective material in medicinal plants, This study tries to investigate on the effect of ecological factors included geographical factors, climatic and edaphic factors. Martial & Methods: This study was collected from 22 different regions in Isfahan and Chaharmahal va Bakhtiari provinces. The composition was determined using high performance liquid chromatography. HPLC chromatograms showed the amount of thymol and carvacrol in every region. Results & Discussion: The highest content of thymol in all investigated samples was recorded in Sheikhshaban region (35.89 mg/g methanol extract) (altitude 2747 m asl) and highest content of carvacrol was recorded in Lark region (23.53 mg/g methanol extract) (altitude 2370 m asl). The results of regression showed that altitude has a positive and meaningful effect on the amount of thymol and does not effect on the amount of carvacrol. All other edaphic factors and climatic factors have no significant effect on the amount of thymol and carvacrol. Cluster dendrogram analysis of the under study regions was drawn according to 3 parameters: the amount of thymol, the amount of carvacrol and the height of the plant (cm), showed the rate of relatedness in samples of different regions, in separate clusters. Conclusion: Thymus daenensis Celak. in Sheikhshaban and Lark in Chaharmahal va Bakhtiari have a close relationship among themselves that have highest amount Thymol and carvacrol.

Keywords: Thymus daenensis Celak. Thymol Carvacrol Medicinal Plants HPLC
Biomass production and heavy metal content of Rosmarinus officinalis grown on MSW compost and cattle manure

Biomass production and heavy metal content of Rosmarinus officinalis grown on MSW compost and cattle manure

Authors: Soheila Kaveh; Majid Fekri; Majid Mahmood Abadi; Naser Boroomand
( 16 downloads)
Abstract

Background & Aim: Rosemary (Rosmarinus officinalis L.) is an evergreen and aromatic plant that is used in pharmaceutical and cosmetic industries-health. Little research has been reported on the greenhouse production of this plant. This paper presents the effects of municipal solid waste compost (MSWC) and cattle manure on rosemary growth in pots at greenhouse. Martial & Methods: Municipal solid waste compost of Kerman city and cattle manure were mixed with soil at rates of 0, 2 and 4 % dry matter basis. The micronutrient and heavy metal contents of the aerial parts of the plant were analyzed to determine nutritional status and heavy metal accumulation. Results & Discussion: Biomass production increased significantly when plants were grown in the municipal solid waste compost and cattle manure. Plants grown on amended soils showed a general improvement in their micronutrient (Fe and Zn) status, yet their heavy metal (Pb and Cd) contents did not increase significantly. Conclusion: The concentration of heavy metals found in the shoots would not significantly increase their transfer from the soil to humans via the food chain.

Keywords: Rosmarinus officinalis Municipal solid waste compost Yield
Study the ethnobotany of medicinal plants in Sirjan, Kerman province, Iran

Study the ethnobotany of medicinal plants in Sirjan, Kerman province, Iran

Authors: Fariba Sharififar; Abed Koohpayeh; Mohammad Mehdi Motaghi; Arezo Amirkhosravi; Elham Puormohseni Nasab; Mansooreh Khodashenas
( 18 downloads)
Abstract

Background & Aim: Since traditional knowledge is base of producing new herbals and other natural products, and old people of ancient cities know about characteristics of such herbals, therefore, death of such people will gradually causes demolishing of their knowledge about herbals. Therefore, it seems it is necessary to register and save such information. The goal of this research is to study and survey about ethnobotany of herbals among people live in Sirjan city in order to learn about way of using these herbals in this area through traditions and customs. Martial & Methods: In this research, at first, the mentioned area divided into different parts by means of geographical maps and then a questionnaire prepared to collect the natives' information about using which parts of herbals in what cases and how to use them. After that, herbals grown in different areas were moved to pharmacy department of Kerman when collected, dried and their herbarium made. Results & Discussion: Finally, 77 species of herbals collected from different areas of Sirjan and registered after identification of each species and their related information (using cases, how and which parts). Due to different cultures of using herbals between natives of Sirjan and other areas of the country and different ways of using various herbals and existence of special herbals in this area, remarkable results about native knowledge of natives using herbals in this area obtained. Conclusion: Considering high potential of herbals in Sirjan, the results of present research and other scientific surveys in this field can provide conditions for better application of herbals in order to prepare products of higher effects and lower harms.

Keywords: Traditional medicine Ethnobotany Herbal Ethnopharmacology
Effects of cultivation condition and storage on dried stigmata of Crocus sativus L. on determination of Crocin

Effects of cultivation condition and storage on dried stigmata of Crocus sativus L. on determination of Crocin

Authors: Kamkar Jaimand; Mohammad Bagher Rezaee; Akbar Najafi Ashtiany
( 18 downloads)
Abstract

Background & Aim: Saffron extract is widely used in the food industry. Saffron (Crocus sativus L.) stigmata contain rare water-soluble carotenoids and the major one is Crocin and this compound have a antitumor in rate and human losomi cells and other model of cancer cells. In this research, we are study on effects of cultivation condition and storage on dried stigmata of Crocus sativus L. on determination of Crocin. Martial & Methods: Samples were collected on November 2006 from two providences (Tehran and Markazi). We kept samples for 20 months dried stigmata of Crocus sativus L . in three different conditions light, dark and refrigerator on zero degree and on November 2008 samples were analysed by High- Performance Liquid Chromatography (HPLC). Results & Discussion: Crocin content from Tehran province (Karaj) in light were 0.029%, dark 0.041% and refrigerator 0.030% and for Markazi province (Khomaine) were in light 0.030%, dark 0.030% and refrigerator 0.028%. Conclusion: With the results of above the best condition to kept dried stigmata of Crocus sativus L. are dark.

Keywords: Crocus sativus L. Crocin Storage condition HPLC
Effect of Morus alba leaf extract on serum glucose and lipids in diabetic rats

Effect of Morus alba leaf extract on serum glucose and lipids in diabetic rats

Authors: Rahmatollah Parandin; Reza Khodarahmi; Shafie Aminimoghadam
( 18 downloads)
Abstract

Background & Aim: Diabetes mellitus is a chronic disease characterized by elevated blood glucose levels and disturbances in carbohydrate, fat and protein metabolism. The objective of the present investigation was to evaluate the therapeutic efficacy of Morus alba leaves in an animal model of diabetes. Martial & Methods: 30 adult male Wistar strain rats (200-250 g) were divided randomly into five groups as follow: (I) healthy control group, (II) healthy control group with mulberry leaf extract treatment, (III) diabetic control group, (IV) diabetic group treated with 600 mg/kg/day of mulberry leaf extract, and (V) diabetic group treated with Insulin. Blood glucose, triglyceride, LDL, HDL and cholesterol were measured at the end of 35 days experiment. Results & Discussion: Administration of Morus alba leaf extract caused a significant decrease in blood levels of glucose (p < 0.001), cholesterol (p < 0.05), triglyceride (p < 0.01) and LDL (p < 0.05), whereas an increase in HDL (p < 0.05) level was seen in diabetic rats. Conclusion: The results of this study showed that Morus alba leaf extract can have significant seffects on blood glucose and lipids in diabetic rats, although further work is needed to elucidate the extent mechanism of these changes.

Keywords: Diabetes Morus alba Lipid Rat
The study of antioxidant potential of Morus alba L. leaves extract

The study of antioxidant potential of Morus alba L. leaves extract

Authors: Parisa Sadighara; Abbas Barin
( 18 downloads)
Abstract

Background & Aim: Applications of synthetic antioxidant in food have side effects. In present study, the antioxidant potential of Morus alba leaves, as natural antioxidant, was screened with cupric ion reducing assay (CUPRAC assay) and inhibition of lipid peroxidation. The aim of this study was to determine the total antioxidant activity of Morus alba leaves. Martial & Methods: The first, total antioxidant activity of Morus alba leaves was determined in two phase; water and methanol extracts by CUPRAC assay and compared with Rosmarinus officinals extract as positive control. In second step, methanol extract of Morus alba leaves was evaluated by lipid peroxidation inhibition of lipids in egg-yolk. CuSo4 induced this lipid peroxidation. Results & Discussion: In CUPRAC assay, Morus alba leaves have antioxidant activity more Rosmarinus officinals. In addition, the methanol extracts of Morus alba leaves can inhibit lipid peroxidation of lipid in egg-yolk. There was significant difference (p ≤ 0.05) between groups. Conclusion: Our results indicated that Morus alba leaves are a good source of natural antioxidants.

Keywords: Morus alba Antioxidant Lipid peroxidation Free radicals
Introductory study of the medicinal plant species of Kazeroon, Fars province

Introductory study of the medicinal plant species of Kazeroon, Fars province

Authors: Mehdi Dolatkhahi; Mehdi Yousefi; Javad Bagher Nejad; Ali Dolatkhahi
( 19 downloads)
Abstract

Background & Aim: Kazeroon, with an area of about 4060 km², is situated at 110 km in the west of Shiraz, Fars province, Iran. This area is important for plant biodiversity, due to the presence of some important habitats such as international Lake of Parishan in the southeast, woodlands of Quercus persica in the east and branches of Shahpoor river in the west of the region. Therefore, for the old antiquity on this city and high biodiversity on plant species; in this work, the medicinal vascular plants were collected, identified and studied for medicinal usages. Martial & Methods: For this purpose, many specimens were collected during the vegetative seasons in 2007 to 2010. All the specimens were prepared as standard herbarium sheets, identified by using available references and stored in the herbaria of Research Institute of Forests and Rangelands (TARI) and Payam Noor University. Life forms and chorological status of the species were analyzed. Results & Discussion: As a result, 90 species belonging to 87 genera and 39 families of angiosperms were reported from the rangelands around the Kazeroon. Lamiaceae, with 11 species, and Asteraceae with 9 species were the largest families respectively, and Plantago (Plantaginaceae) with 3 species was the largest genus in the medicinal flora of this area. Conclusion: The presence of more than 90 medicinal plant species indicates high biodiversity in the studied region. Furthermore, the findings of this investigation are completely in conformance to the conditions of the area that has a semi-arid climate with dry summers and low rainfall.

Keywords: Flora Ethnobotany Medicinal plants
Investigation of input energy efficiency in dill (Anethum graveolens L.) farming in Rodehen region

Investigation of input energy efficiency in dill (Anethum graveolens L.) farming in Rodehen region

Authors: Naser Hosseini; Elham Tavakoli Dinani
( 18 downloads)
Abstract

Background & Aim: Energy is one of important debates in agriculture ecology and for this reason; the ratio of output and input energy in different agriculture ecosystems has been calculated. If one can reduce, input energy level into farms through the indices like poisons, fertilization, tractor energy and lab our force. In addition to the net income of the farmers, this issue would play a significant role in preserving farm ecosystem from pollution and wrecker factors. Martial & Methods: For this reason, energy balance sheet in dill farms as well as input and output energy in 2009-2010 researched by distributing and questionnaire among farmers Rodehen region. Then, the input energy amount into farms via energy-consuming factors, mentioned above, with regard to special coefficients was computed. Energy was computed based on seed function, chemical compound and its content as well. Results & Discussion: In this investigation, evaluated the level of stored energy 64668971.48 kcal per hectare and level of output energy 804640 kcal per hectare. Energy efficiency on the basis of seed function 0.011 were estimated that the greatest part of energy depended on irrigation and nitrate fertilizer that with right management may reduce consumptive energy in farm and nitrate fertilizer and, on the other hand, to increase balance sheet.

Keywords: Dill Output and input Energy Efficiency
The methodology of research in Traditional Medicine

The methodology of research in Traditional Medicine

Authors: Majid Avijgan; Maedeh Moheb Nasab
( 18 downloads)
Abstract

In countries having traditional medicine (TM), one of the main challenges for any researcher is research methodology. Current methodologies are different with what was in past. The main purpose of this article is to present the steps (herbs, claims and methodology) of research in TM fields. 1. Assessment of herbs History, method of study, quality assessment, efficacy, safety, toxicity and therapeutic effect are included in this part. 2. Efficacy and safety of herbs Botany, therapeutic effect, toxicology methods, how to study toxicity will be explained in this part. 3. Assessment of TM products This part contains herb identification, certification, standardization, claims for therapeutic effect, confirmation of safety of herb. 4. Claims for efficacy of herbs It includes various claims, concept, features, base, importance, and evidence to confirm these claims. 5. Method of study This includes for in vitro/in vivo studies (observational and interventional). In addition, the role of Meta analysis will be discussed. 6. Ethical committee Ethics in research, ethical committee, their activity, check list of committee for any study will be explained.

Keywords: Ethnomedicine Medicinal plants Methodology Botany
Effect of Diospyros kaki L. fruit extract on gag reflex

Effect of Diospyros kaki L. fruit extract on gag reflex

Authors: Elham Shadmehr; Ehsan Hekmatian; Gholam Reza Asghari
( 18 downloads)
Abstract

Background & Aim: A gag reflex (GR) can be a problem to compliance and delivery of dental treatment. The aim of this study was to evaluate the use of Diospyros kaki L. fruit extract in controlling gag reflex during dental treatment. Experimental: Our study was a randomized double blind controlled trial with convenient sampling on 84 patients that is candidate for radiographic procedures in Dental School, Isfahan University of Medical Sciences. Randomization procedure entered in each group of intervention with Diospyros kaki L. extracts or placebo. Before and after intervention gag reflex was categorized in 4 score (0 to 3) and evaluated. Data analysis and comparing performed with SPSS software and Chi-square and McNamara tests. Results & Discussion: Gag reflex in soft palate region & tensile was found on all patients. After intervention the decrease on gag reflex was recorded 97.6 and 100 percent for case and 19.4 and 16.6 percent for control group on soft palate region and tensile respectively. Statistical significant decreased between intervention (case) & placebo groups (pIndustrial and practical recommendations: Our results indicate that consumption of Diospyros kaki L. extracts are seems to be an effective method of controlling gag reflex during dental treatment. It can be a confidence method to use on dental procedures especially radiographic.

Keywords: Gag reflex Diospyros kaki L. Extract Dental procedures
Efficiency of Echinacea purpurea L. on total antioxidant activity in serum of broiler chicks

Efficiency of Echinacea purpurea L. on total antioxidant activity in serum of broiler chicks

Authors: Gholam Reza Ghalamkari; Nasir Landy; Majid Toghyani; Fariborz Moatar; Abbas Abed Esfahani; Maryam Araj Shirvani
( 19 downloads)
Abstract

Background & Aim: This experiment was conducted to examine the effect of different levels of Echinacea purpurea (EP) in comparison with an antibiotic (flavofosfolipol) on total antioxidant activity (AOA) in serum of broiler chicks. Experimental: In this trial 240 one-day-old broiler chicks (Ross 308) were weighed and randomly assigned to the 5 treatment groups, each with 4 replicates with 12 broilers. The 5 treatments were as follows: 1. Basal diet (control); 2. Basal diet + antibiotic (4.5 mg flavofosfolipol/kg diet); 3. Basal diet + dried aerial part powder of EP (5 g/kg diet); 4. Basal diet + dried aerial part powder of EP (10 g/kg diet); 5. Basal diet + tincture extract (0.25 g/kg diet). The contents of Flavonol-o-glycosides as Quescetin was determined by spectrophotometer method, and the amount of Flavonol-o- glycosides as Quescetin in 5 g/kg diet EP to alcoholic extract was equal. At 42 days blood sample was taken and analyzed for total antioxidant activity (AOA) of serum blood. Results & Discussion: The results showed that using of 10 g/kg diet EP led to the highest AOA (m mol/lit) compared to other groups. Alcoholic extract supplementation to diet resulted higher AOA than those control and antibiotic treatments but not significant. The AOA increased in broilers fed diet containing 5 g EP/kg diet than those control, Alcoholic extract and antibiotic treatments but not significantly. Industrial and practical recommendations: The results of this trial showed that, using of 10 g EP/kg diet improved total antioxidant activity in serum of broiler chicks. According to the risk of producing the microbial population resistant to antibiotic because of continuous use antibiotics in animals diet in fields and due to the findings of this experiment and other experiments, the powder of the top organs of Echinacea purpurea can be used as a suitable alternatives for antibiotic in food diet of the poultry.

Keywords: Echinacea purpurea Antioxidant activity Broiler Serum
Morphological & anatomical study of Salvia macrosiphon Boiss

Morphological & anatomical study of Salvia macrosiphon Boiss

Authors: Gholamreza Bakhshi Khaniki; Elham Moghassemi
( 18 downloads)
Abstract

Background & Aim: Salvia macrosiphon is one of the important species of Salvia which belongs to the Lamiaceae family. All 58 Iranian species of Salvia grow in different ecological places. The aim of this research is the investigation of morphological and anatomical characteristics of S. macrosiphon. Experimental: The above–mentioned species were collected from Zavarijan and Dodangeh region in Borojerd in 2007, and were transferred into a suitable place and then they have been determined systematically and they were used for morphological and anatomical studies by using light microscope. Results & Discussion: The investigation shows the species are mostly similar to the other ones previously studied anatomically. There were many trichomes in epidermal layer of stem. There are also anantomically different bundle sheath in pedicles which is three in middle and two in surrounding area in S. macrosiphon. The collenchyma tissues were observed in corners of stem. Parenchyma cells have chloroplasts and there are also many trichomes in the surface of leaves which seems many of them are secretary. Industrial and practical recommendations: The usage of the extract of different species of Saliva macrosiphon in medicinal and food products and its biological activity totally depends on the chemical compounds of extract. So, according to the importance of these extracts, doing some extensive research on all Iranian species is recommended.

Keywords: Salvia macrosiphon Morphology Anatomy
The effect of Hypericum scabrum on the hematologic factors, body weight and temperature in mice

The effect of Hypericum scabrum on the hematologic factors, body weight and temperature in mice

Authors: Abdollah Ghasemi Pirbalouti; Mohsen Jafarian Dehkordi; Rahman Poorhakim Davoodi; Behzad Hamedi; Mohammad Rabie
( 18 downloads)
Abstract

Background & Aim: Vast variety of plants in various regions of the country and lack of enough information on their chemical combinations, sometimes lead to triggering poisoning and unsatisfied complications. Regarding to fabulous herbal characteristics of Hypricum, many research about poisoning and side effects of high concentrations of H. scabrum have not taken place until now. Therefore regarding to above mentioned issues, current study has done due to evaluating poisoning effects of H. scabrum on behavioral properties of mice. Experimental: In an experimental study, first H. scabrum collected from Sabz-e-Kooh mountains, Chaharmahal va Bakhtiari province. There were five 4 mice-group that has taken 100, 250, 500 and 1000 mg/kg H. scabrum extract and one group didn’t get anything. Lastly, after 24 hours various hematologic, weight, and temperature characteristics have been evaluated. Also, like the past method these properties were evaluated for 14 days after taking extracts. Results & Discussion: In pathologic evaluation of kidney and liver, no obvious difference was seen. In statistical analysis of the results about HCT, Hb, RBC, Mono, MCV, Band, MCH, MCHC and PH no significant differences obtained between case groups and control group. About WBC, neutrophils and eosinophils count significant difference was gathered (p<0.05), that the reason was physiologic stress due to high dosage of the drug; because band cells (immature neutrophils), marker of infection and bone marrow response, has not decreased. Industrial and practical recommendations: Totally in current study it seems that H. scabrum extract, in none of the concentration used, have poisoning effect and just can lead to stress profile in subjects. But regarding the body weights after 2 weeks of experiment, it can be concluded probably the plant was lead to weight gain. Entirely H. scabrum had not any harmful effects but pathologic ones on liver in high concentrations.

Keywords: Hypericum scabrum L. Body weight Body temperature Hematologic factors Toxicology
Genetic improvement of essence percent and dry flower yield using indirect selection in German chamomile (Matricaria chamomilla L.)

Genetic improvement of essence percent and dry flower yield using indirect selection in German chamomile (Matricaria chamomilla L.)

Authors: Ahmadreza Golparvar; Abdollah Ghasemi Pirbalouti
( 17 downloads)
Abstract

Background & Aim: German chamomile is one of the most important medicinal plants. So, assessment of genetic diversity and relationship among the traits are very essential in chamomile breeding programs. Determination of the best indirect selection criteria for genetic improvement of essence percent and dry flower yield of German chamomile (Matricaria chamomilla L.) populations was investigated using some morphological, agronomical and phonological characteristics. Experimental: In this experiment, statistical design of RCBD with three replications was used. Number of flower plant-1, fresh flower yield plant-1, days to budding, days to 50 and 100% of flowering, number of flowering stem, plant height, number of tiller plant-1, dry flower yield plant-1 and essence percent were measured. Results & Discussion: Analysis of variance showed highly significant differences among chamomile populations for all the studied traits. This assigns genetic diversity for mentioned traits and possibility of genetic improvement of these via selection. Assessment of correlation coefficients revealed positive and significant relationship of the majority of traits with dry flower yield as well as some traits with essence percent. Path analysis indicated applicability of indirect selection through the traits days to 50% flowering, No. flower plant-1, fresh flower yield plant-1 and days to budding for genetic improvement of dry flower yield specifically in early breeding generations. Industrial and practical recommendations: The traits 50% flowering and No. flower plant-1 also were introduced as the best indirect selection criteria for improvement of essence percent based on path analysis results.

Keywords: Matricaria chamomilla Genetic diversity Indirect selection Selection index Path analysis

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