Journal of Herbal Drugs

Journal of Herbal Drugs

Basic info

  • Publisher: Islamic Azad University, Shahrekord Branch
  • Country of publisher: iran, islamic republic of
  • Date added to EuroPub: 2018/Feb/04

Subject and more

  • LCC Subject Category: Marketing, Agricultural Science, Biotechnology, Botany, Genetics, Plant Sciences, Medicine, Pharmacology, Toxicology
  • Publisher's keywords: Herbs, Cultivation or Agronomy, Breeding, Biotechnology, Marketing and Economy, Medicinal Plants, Genetic
  • Language of fulltext: english, persian
  • Full-text formats available: PDF

Publication charges

  • Article Processing Charges (APCs): No
  • Submission charges: No
  • Waiver policy for charges? No

Editorial information

Open access & licensing

  • Type of License: CC BY
  • License terms
  • Open Access Statement: Yes
  • Year open access content began: 2011
  • Does the author retain unrestricted copyright? False
  • Does the author retain publishing rights? False

Best practice polices

  • Permanent article identifier: DOI
  • Content digitally archived in: Nopolicy
  • Deposit policy registered in: None

This journal has '260' articles

Effect of jasmonic acid and salicylic acid on polyphenol and flavenoids in extract of Calendula officinalis L. flower

Effect of jasmonic acid and salicylic acid on polyphenol and flavenoids in extract of Calendula officinalis L. flower

Authors: Abdollah Ghasemi Pirbalouti; Seyed Abbas Mosavi Haris; Farhang Tirgir; Behzad Hamedi
( 15 downloads)
Abstract

Background & Aim: Marigold or Calendula officinalis L. is a annual herb belongs to the Asteraceae family. Marigold is a valuable medicinal plant which is used in pharmaceutical industry. In addition, this plant is cultivated as an ornamental plant. Aim of current study was to evaluate the effect of different concentrations of jasmonic acid (JA), and salicylic acid (SA) on phytochemical properties of Calendula officinalis L. flower. Experimental: A pot experiment was conducted in a completely randomized design with six treatments, and seven replications. The treatments, including four concentrations of SA (1, 10, 20, and 40 μmol/L), and JA in three levels (50, 100, and 200 μl/L). The treatments were sprayed before the early flowering stage of growth. Results & discussion: Results of analysis of variance indicated the various concentrations of the foliar application of JA, and SA do have significant impacts on polyphenol, carotenoid and flavenoids contents in the extracts of C. officinalis. In addition, results indicated the correlation between traits by Pearson method that there was a significant and positive relation between polyphenol and carotenoid (0.603**). Industrial and practical recommendations: In metabolic cultivation, for producing a special metabolite, the main agronomic and processing management should be regarded in order to increase the rate of essence and metabolites. Finally, the treatment of solution of JA 100 μl may be suitable because of increased content of carotenoid and polyphenol contents.

Keywords: Calendula officinalis L. Jasmonic acid Extract Salicylic acid
Effect of drought stress on some physiological properties and antioxidant activity of Achillea tenuifolia Lam

Effect of drought stress on some physiological properties and antioxidant activity of Achillea tenuifolia Lam

Authors: Shima Gharibi; Badraldin Ebrahim Sayed Tabatabaei; Ghodratollah Saeidi; Sayed Amir Hossein Goli; Majid Talebi
( 16 downloads)
Abstract

Background & Aim: Osmotic stress in plants lead to increase free radicals and plants use different mechanisms to scavenge these radicals. So, researchers apply stresses especially drought stress to increase secondary metabolites such as phenolics, and antioxidants. One of the valuable medicinal plants is yarrow (Achillea tenuifolia) which is a perennial plant with different medicinal applications. Experimental: In order to assess the effect of drought stress, four different treatments (25%, 50%, 75% and 100% of Field Capacity) with four replicates was done in plastic pots at greenhouse. After 30 days, leaves of samples were used to evaluate total phenolics, antioxidant activity using three model systems including 1,1-diphenyl-2-picrylhydrazy (DPPH), ferric thiocyanate (FTC), and β-carotene-linoleic acid assay. In addition, malone dialdehyde (MDA), and proline content were evaluated. Results & Discussion: Drought stress in A.tenuifolia significantly increased total phenoloics, and antioxidant activity (in DPPH and β-carotene-linoleic acid assay). In addition, proline and malone dialdehyde were elevated by stress, while according to FTC model, there was no significant differences between 25% and 50% FC treatments.

Keywords: Achillea tenuifoilia Drought stress Antioxidant activity
Effect of ecological factors on chemical compounds of Verbascum songaricum leaves

Effect of ecological factors on chemical compounds of Verbascum songaricum leaves

Authors: Vahid Karimian; Mohammad Reza Vahabi; Mohamad Fazilati; Mostafa Tarkesh
( 15 downloads)
Abstract

Background & Aim: Verbascum songaricum is a perennial herbaceous belongs to the Scrophulariaceae (snapdragon) family. Current study was done to study the environmental conditions effect on phytochemical properties of Verbascum songaricum leaves for extracting the effective materials. Experimental: This study was conducted at five range sites, including Hoze valley, Ghahiz, Someirom, Ghale Gadam, and Dena in two provinces (Isfahan and Kohghiluyeh va Boyer Ahmad) Iran. The specimens were collected in flower stage on July 2011. Leaves extract was obtained using digestion method and then analyzed by GM-MS to identify the main compounds in extract. Results & Discussion: Results indicated the ketone and alcoholic compounds in Ghazis and Someirom and Dena were the higher than Hoze Valley and Ghale Gadam regions. Soil pH was as an important ecological factor affect on the main components in the extract of V. songaricum leaves. The highest amount of hydro-carbonic and amine compounds detected in Ghazis and Someirom and Dena regions.

Keywords: Verbascum songaricum Environmental factors Extract Range
Effect of seasonal variation on essential oil yield, and morpho-physiological properties of Achillea filipendulina Lam

Effect of seasonal variation on essential oil yield, and morpho-physiological properties of Achillea filipendulina Lam

Authors: Elham Zeinali; Mehdi Rahimmalek
( 14 downloads)
Abstract

Background & Aim: Achillea filipendulina is one of the most important species of the family Asteraceae and, it considered as one of the most valuable medicinal and ornamental plants. Environmental factors affected on quality and quantity of the essential oil of medicinal and aromatic plants. So, selecting of appropriate season for harvesting can lead to increase quality and quantity yield. The aims of the present study were to assess the effect of seasonal variation on essential oil yield and some morphophysiological traits of A. filipendulina. Experimental: In this research, split plot experiment based on complete block design was conducted in three replicates. The aerial parts were harvested and the essential oil extracted by Clevenger approach in different seasons. Results & Discussion: Afc genotype showed the lowest amount concerning the plant height, leaf length and leaf width in winter, while Af21 had the highest height and leaf width in summer. The essential oil yield varied between 0.01 to 0.84% in all seasons. The highest and the lowest essential oil yield belonged to Afc in summer and Af21 in winter, respectively. The lowest and the highest hydrogen peroxide accumulation were in Af21 in spring and Afc in summer, respectively. Furthermore, malonede-aldehide (MDA) accumulation varied from 0.3 to 3.37 ng/fw. Afc in spring and Af21 in summer showed the lowest and the highest MDA, respectively. Recommended applications/industries: According to the results of present study, in order to increase dry matter and essential oil yield of Achillea filipendulina, harvesting for essential oil extraction is suggested in early summer.

Keywords: Achillea filipendulina Seasonal variation Essential oil
Systematically study of medicinal plants in Bushehr province, Southern Iran

Systematically study of medicinal plants in Bushehr province, Southern Iran

Authors: Mehdi Dolatkhahi; Iraj Nabipour
( 15 downloads)
Abstract

Background & Aim: Bushehrwith an area of about 177.1km² is situated in center of Bushehr province, southern Iran. Existence beach line with Persian gulf and Helle river cause of settlement diversity in this zone. With attention in this settlement diversity in this zone transaction of this work is necessary. Experimental: Many specimens were collected during the vegetative seasons in 2011to 2013. All the specimens were prepared as standard herbarium sheets, identified by using available references flora and stored in the herbarium of Medical Sciences University Bushehr Center. An analysis was made of the species used, parts of the plant employed, preparation methods, administration means, and the ailments treated in relation to pathological groups. . Results & Discussion: According to results, in study area about 63 species belonging to 55 genera and 36 families have been recognized. The largest family of the region is Asteraceae with nine species. Plantago genus with five species is the largest genus among the existing genera. Recommended applications/industries: According to results of this study, the presence of more than 63 medicinal plant species indicated high biodiversity in the studied region (Bushehr).

Keywords: Bushehr County Medicinal Plants Systematically study Ethnopharmacology
A review on botany and ethnobotany of NepetabracteataBenth. grown in KhorasanRazavi province

A review on botany and ethnobotany of NepetabracteataBenth. grown in KhorasanRazavi province

Authors: Hajar Mellati; Mohammad Kafi; Fereydon Mellati; Farzad Najdafi
( 15 downloads)
Abstract

Background & Aim: Nepetabracteata Benth is a medicinal plant belongs to the Lamiaceae family which wildly grows in Khorasan province. This herb is used by the indigenous people as afolkloric medicine in Khorasan. This paper aimed to study the situation and application of this plant in traditional medicine of Khorasan province. Experimental: Current study was done by questionnaire and interview with apothecaries andvillagers living near the natural habitats of N.bracteatain spring to summer 2012. Results & Discussion: Results of this study indicated that the aerial parts, especially the flowers of N.bracteata are used by the indigenous people for treatmentof many diseases, including asthma, cold, headache, and stress. In addition, this herb has used as a sedative. The flowers of N.bracteataare used for treatment of respiratorydiseases, including asthma, lungspasms, seasonalallergies, and coughsdue tocold, chesttightnessorcongestion, wheezing, chronic inflammation of the respiratory tracts, tonsillar infection, even lung cancer, neurological disease, stress,digestivediseases including stomachache, colic, stomachandintestinal infections, and forremoving body weakness and strengthening theimmune system, preventing fromhair loss and relievingmenstrualirregularity. The most common preparation methods are brewing, boiling and distillation. Recommended applications/industries: This paper having investigated the native and traditional usages of N.bracteata which can provide valuable research fields for researchers to remove disambiguation about using this plant and provide its widespread domestication and utilization field based on native knowledge and modern technologies.

Keywords: Ethnopharmacology Nepetabracteata Traditional medicine Herb
Phytochemical diversity on essential oils from Myrtus communis leaves of different populations collected from Fars and Kohkeloyeh va Boyerahmad provinces

Phytochemical diversity on essential oils from Myrtus communis leaves of different populations collected from Fars and Kohkeloyeh va Boyerahmad provinces

Authors: Leyla Mehravar; Gholamreza Bajhian; Abdollah Ghasemi Pirbalouti; Mojtaba Jafarnia
( 14 downloads)
Abstract

Background & Aim: Myrtle (Myrtus communis L.), is an important medicinal plant that is used for pharmacological uses and conservation of environments (for example preventing the soil erosion) regards to its specific condition habitat. Experimental: In this research, phytochemical variations of the essential oils from different populations of myrtle collected from Fars (Saydan, Cheshme-Ali, and Simakan), and Kohkeloyeh va Boyerahmad (Dehdasht and Gachsaran) provinces using GC-MS were analyzed. Results & Discussion: Results of GC/MS analysis indicated that α–pinene, 1,8–cineole, linalool, linalyl acetate, α–terpineol, and linalool oxide were the main components in the essential oils from all populations. The essential oils from the leaves of myrtle were characterized by high levels of oxygenated monoterpenes, hydrocarbon monoterpenes, phenylpropanoids and sesquiterpenes. Monoterpenes were the main constituents of the essential oil of the leaves of the collected plants. Cluster analysis based on Euclidean distance square by UPGMA method classified the samples into three groups. In this classification, samples referred to the Gachsaran and Dehdasht populations (Kohkeloyeh va Boyerahmad province), and the Saydan population (Fars province) were at the same group. Recommended applications/industries: Results indicated the main source of variability in chemical composition and oil yield of the studied populations seemed to be due to differences in environmental conditions and chemotypes.

Keywords: Myrtle Natural habitats Essential oil Chemotype
Effect of the extract of Hypericum perforatum on digestive organs morphometry in Wistar rats

Effect of the extract of Hypericum perforatum on digestive organs morphometry in Wistar rats

Authors: Maryam Modhej; Saleh Tabatabaee Vakili; Mohsein Sari; Somayeh Slari; Esrafil Mansuri
( 14 downloads)
Abstract

Background & Aim: St John's wort (Hypericum perforatum L.) contains hypericin and hyperforin as the main components of the extract that binds with GABA and sigma opioid receptors. This herb has many pharmacological effects, including analgesic, sedative, soothing, antispasmodic, anticonvulsant, anti-depressant, and anti-bacteria. In this study examined the effect of two concentrations of Hypericum perforatum extract on digestive organs morphometric in male Wistar rats. Experimental: Among the 54 rats tested with six repetitions, effect of Hypericum perforatum extract was assessed in three groups. Experimental treatments were control (receiving water), groups two and three that received Hypericum perforatum extract (250 and 500 mg /kg.bw) respectively. Rats were treated with Hypericum perforatum for 03days, through the Gavage method Results & Discussion: Results indicated that big intestine weight in the 250 mg/kg.bw Hypericum perforatum treatment significantly was more than the control group (p ≤ 0.05), and also the length of big intestine was taller in 250 and 500 mg/kg.bw treatments than control group (p ≤ 0.05). Recommended application: According to results, the extract of Hypericum perforatum can use for weight increasing.

Keywords: Hypericum perforatum Morphometric Digestive organs Rat
Effects of essential oils of Thymus deanensis and Satureja bachtiarica on plasma lipoproteins in rats feeding with a fatty diet

Effects of essential oils of Thymus deanensis and Satureja bachtiarica on plasma lipoproteins in rats feeding with a fatty diet

Authors: Mehrnoush Nazari; Ramesh Monajemi; Abdollah Ghasemi Pirbalouti; Mohsen Jafarian Dehkordi; Majid Riahi Dehkordi
( 15 downloads)
Abstract

Background & Aim: Hyper lipidemy is one of the main factors in progressing cardiovascular diseases. Thymus deanensis celak and Satureja bachtiarica Bunge are medicinal herbs which are used in folklore medicine in Iran. In this research, hypolipidemic effects of essential oils of these herbs in rats fed with a fatty diet were investigated. Experimental: 40 male and femade adult rats (20 rats in each group) with 190 - 220 g weight were divided to five groups randomly (8 rats in each group). Experimental groups were 1) control, 2) control + fatty ration, 3) standard drug () + fatty ration, 4) T. deanensis (200 mg/kg) + fatty ration, and 5) S. bachtiarica (200 mg/kg) + fatty ration. At one week after starting special dietary ration, animal treated by the essential oils for three weeks. In final, serum and plasma were separated for measuring lipids and doing the other biochemical experiments. Results & Discussion: Results indicated that the essential oil of T. deanensis in rats fed with fatty dietary ration decreased level of low density lipoproteins (LDL) significantly (p ≤ 0.05). There was a significant difference in amount of triglycerides of blood serum in rats (p ≤ 0.05), The lowest and highest amounts of triglycerides obtained from T. deanensis and control + fatty ration groups, respectively. Recommended applications/industries: Results indicated the essential oil of T. deanensis had hypolipidemic effect in rats fed with a fatty diet.

Keywords: Plasma lipids Savory LDL HDL Thyme
Antioxidant activity of essential oil of Heracleum lasiopetalum fruits on chemical properties of potato chips

Antioxidant activity of essential oil of Heracleum lasiopetalum fruits on chemical properties of potato chips

Authors: Leila Sedaghat Boroujeni; Mohammad Hojjatoleslami; Javad Keramat; Abdollah Ghasemi Pirbalouti
( 14 downloads)
Abstract

Background & Aim: Chemicals antioxidants and lipid oxidation products are known as cancer-causing factors in food systems. In this study, the effect of essential oil from Heracleum lasiopetalum fruits on lipid oxidation and physicochemical properties of potato chips in comparison with commercial antioxidant has been investigated. Experimental: The essential oil of H. lasiopetalum extracted using a Clevenger-type apparatus, and analyzed by GC/MS. The essential oil was added to the frying oil of potato chips in concentration level 3000 ppm, and its antioxidant effect on produced chips was analyzed by peroxide value, TBA and acidity of the essential oils from potato chips. BHA and TBHQ were added as the commercial antioxidant in 200 ppm and antioxidant reduction evaluated in 45 days period. Results & Discussion: Results indicated the essential oil of H. lasiopetalum fruits could reduce oxidation of potato chips the same as synthetic antioxidants. TBA test indicated the essential oil of H. lasiopetalum is higher effective than BHA in reduction of the primary TBA reaction but TBHQ is the lowest. Recommended applications/industries: The essential oil of H. lasiopetalum had antioxidant effect which it can use as natural antioxidant in foods during storage.

Keywords: Potato chips; Essential oil; Heracleum lasiopetalum; Lipid oxidation; Antioxidant
Oleuropein content in olive leaves extract of sponge cake

Oleuropein content in olive leaves extract of sponge cake

Authors: Fariba Ataei; Javad Keramat; Mohammad Hojjatoleslami; Maryam Mirlohi
( 13 downloads)
Abstract

Background & Aim: Oleuropein has pharmacologic properties and is the main component of olive leaves which is considered to be the most pharmacologic compounds of olive (Olea europaea L.). The aim of this work was to investigate the possible using of the extract of this plant in food industry (sponge cake) in order to take advantage of its medicinal properties. Experimental: Ethanolic extract of olive leaves was added to sponge cake formula (0, 0.5, 1, 1.5, and 2 for 100g flour) and oleuropein content of the samples was determined using HPLC. In addition, the sensory qualities of the samples, such as taste, off flavor, texture, color, odor and overall acceptability were measured by a five point hedonic sensory test which performed by twenty panelists. Results & Discussion: According to the sensory evaluation, no significant difference in respect to taste and off flavor was found between the samples containing 0.5 g of extract and the reference samples. Furthermore, no significant difference was observed between the samples containing 0.5 and 0.2 g extract and reference samples in respect to the texture. On the whole the sample containing 0.5 g extract was the only product that showed to be accepted by the panelists contained 0.003 g (63 ppm) oleuropein was presented. There was no significant difference between the samples, including reference in respect to their protein, fat and mineral contents. Recommended applications/industries: Olive leaves containing oleuropein and rich in phenolic compound having pharmacologic properties could be used in food industry (sponge cake).

Keywords: Oleuropein; Extract; HPLC
The effects of placement position and corm size of saffron (Crocus sativus L.) on stigma and corm yields in Ankara conditions

The effects of placement position and corm size of saffron (Crocus sativus L.) on stigma and corm yields in Ankara conditions

Authors: Neşet Arslan; Arif Ipek; Amir Rahimi; Gökhan Ipek
( 14 downloads)
Abstract

Background & Aim: Saffron (Crocus sativus L.) formerly was important in Turkey. Saffron cultivation has been decreased and it is now only cultivated in three villages in this country. It is triploid and exclusively propagated in a vegetative way by corms. In Turkey, saffron is traditionally planted by placing corms in rows randomly without grading or sorting; which results in placement of corms in vertical, horizontal and reverse in rows at random. The study aimed to find the effect of corm size and position of placement in rows on stigma and corms yield. Experimental: This study was done at the experimental fields of the Department of Field Crops, Faculty of Agriculture, Ankara University, during 2010-2011 using four different corms size and three placement positions in three replications. Results & Discussion: The results revealed that position of corms and their size had significant effect on stigma yield. Whereas, corm yield was influenced by corm size only. Recommended applications/industries: According this study, vertical placement produced more stigma yield than other ones in planting. Vertical placement corms in rows should be practiced to obtain more stigma yield.

Keywords: cultivation; Crocus sativus L; Vertical placement; Stigma
Phytochemical response of hyssop (Hyssopus officinalis L.) to foliar application of jasmonic acid

Phytochemical response of hyssop (Hyssopus officinalis L.) to foliar application of jasmonic acid

Authors: Abdollah Ghasemi Pirbalouti; Abolghasem Gorgij; Mehdi Rahimmalek; Behzad Hamedi
( 15 downloads)
Abstract

Background & Aim:Jasmonic acid (JA) is regarded as endogenous regulators that play important roles in regulating stress responses, plant growth and development.Effect of foliar application of JA on the essential oil and oil chemical components of hyssop (Hyssopus officinalis L.) were investigated. Experimental: This study conducted in a CRD with three replications and in experimental greenhouse, I.A.U., Shahrekord Branch, Iran at 2012. Experimental treatments included (I) water foliar application (control), (II) water + aceton foliar application (as a solvent), (III-V) 50, 100 and 200 JA µL. The essential oils obtained by hydro-distillation were analyzed by Gas Chromatography-Mass Spectrometry. Results & Discussion: The results of GC-MS showed that the major components of the oil were cis-3-pinanone (10-39%), trans-3-pinanone (4-28%) and β-pinene (27-34%). The results of analysis of variance of the experiment showed that different levels of the foliar application of JA do have significant impacts on chemical constitutes in the essential oil.Finally, foliar application of 200 µL JA on some of secondary metabolite production in H. officinalis oil could be partially changed. Recommended applications/industries: Abbreviation: JA: Jasmonic Acid, MJ: Methyl Jasmonate, GC-MS: Gas Chromatography-Mass Spectrometry µL: Micro liter, M: Molar; ANOVA: Analysis of Variance, CRD: Completely Randomized Design.

Keywords: Hyssopus officinalis L; Jasmonic acid; Essential oil; GC-MS
Phytochemical and antimicrobial activity of Monechma ciliatum (black mahlab) seed extracts

Phytochemical and antimicrobial activity of Monechma ciliatum (black mahlab) seed extracts

Authors: Oshi M.A.M; Abdelkareem A.M; Eltohami M.SH
( 14 downloads)
Abstract

Background & Aim: The purpose of present study was to examine and validate the folk's claim of inhalation of Monechma ciliatum seeds powder by traditional African natives for cold and allergic conditions, so as to formulate a useful therapeutic agent to respiratory tract infections. Experimental: Different extracts were bio-assayed in vitro for their bioactivity to inhibit the growth of pathogenic bacteria and fungi. Bacteria and fungi selected in the study were common pathogens for respiratory tract infections. Results & Discussion: Klebsiella pneumoniae was highly sensitive to the hydroalcoholic extract (maceration by 70% ethanol and 30% water) and moderately sensitive to the extract (maceration by water). Staphylococcus aureus was found to be moderately sensitive to the hydroalcoholic extract (maceration by 70% ethanol 30% water). Pseudomonas aeruginosa was resistance to all extract used. In addition, all fungi used were found to be resistance to all extracts. Phytochemical screening test results of seeds of Monechma ciliatum to detect the major constituents showed the presence of flavonoids, tannins, triterpens, and anthraquinones. The findings of study support the traditional uses of the plant in the therapy of respiratory tract infections. Recommended applications/industries: The extracts of black mahlab could be used in future direction as alternative therapeutic agents for the treatment of human's respiratory tract infectious diseases caused by Klebsiella pneumoniae and Staphylococcus aureus.

Keywords: Black mahlab Monechma ciliatum Antibacterial Activity Antifungal Activity
Collection and identification of medicinal plants used by the indigenous people of Mobarakeh (Isfahan), southwestern Iran

Collection and identification of medicinal plants used by the indigenous people of Mobarakeh (Isfahan), southwestern Iran

Authors: Shahin Mardaninejad; Mahin Janghorban; Mansoreh Vazirpour
( 13 downloads)
Abstract

Background & Aim: Knowledge of the traditional application of plants is declining faster than the plants themselves; this study was conducted to record and store the local knowledge and cultural outcomes for using the medicinal plants in treating diseases in Mobarakeh region, Isfahan, Iran. Experimental: This study has done based on applying the desert survey, information of local people, and identification, classification and introducing these plants. Then the plant species were collected and transferred to the department of botany in Isfahan Research Center for Natural Resources in order to be identified after drying and preparing their herbarium. Results & Discussion: Finally, 200 plant species were identified; from which 75 ones, belonged to 73 genera, and 33 families with medicinal properties, were identified. From this number, 75% are herbaceous, ten percent shrubby and 15 percent are arboreous. The highest number of medicinal species belongs to the Lamiaceae family with nine species, Asteraceae family with eight species, Rosaceae family with six species, and the families Apiaceae, Papilionaceae, and Brassicaceae with five species. These plants are used in traditional medicine for treatment of gastrointestinal ailments, relaxation, cough, diarrhea, low blood sugar, and hyperlipidemia. Recommended applications/industries: According to results of this study, the preservation and conservation of some herbs species is essential. This document can play a role in preserving the indigenous knowledge of using these plants.

Keywords: Ethnobotany Medicinal plant Ethnopharmacology

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