Hypolipidemic Activity of Spinacia Oleracea L. in Atherogenic Diet Induced Hyperlipidemic Rats.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2012, Vol 1, Issue 1
Abstract
Spinacia oleracea (spinach) of family Amaranthaceae is an important plant used traditionally for medicinal purposes. Hyperlipidemia was induced by treated orally with atherogenic diet. In atherogenic diet induced hyperlipidemic model, the rats receiving Spinacia oleracea powder showed significant reduction in total cholesterol, triglycerides, total protein and elevation of high density lipoprotein cholesterol. Spinacia oleracea was found to possess significant hypolipidemic activity. The results also suggest that Spinacia oleracea powder at 200mg and 400 mg/kg b.wt. concentrations are an excellent lipid-lowering agent.
Authors and Affiliations
Ranjan Kumar Giri*| Institute of Pharmacy and Technology, Salipur, Cuttack – 754202, India., Sunil Kumar Kanungo| Institute of Pharmacy and Technology, Salipur, Cuttack – 754202, India., Niroj K. Tripathi| Department of Zoology, Berhampur University, Berhampur, Ganjam, Odisha, India.
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