Bacteriological spectrum and antibiogram of cholelithiasis
Journal Title: Medpulse International Journal of Surgery - Year 2017, Vol 3, Issue 1
Abstract
Background: Different microbes in the bile may be cause to post-cholecystectomy infections. Systemic bacteremia may occur in severe cases. Thus, understanding the most common organisms causing them and their antibacterial susceptibility pattern would be useful in prevention of these infections. The present study aimed to find outthe microbial flora in the bile of patients with cholecystitis and cholelithiasis and also to study their antibiotic susceptibility patterns. Material and Methods: A total of 100 elective cholecystectomy patients with gall bladder stones were included.Patients underwent laparoscopic or open cholecystectomy depending on their choice. Bile from removed specimen of gall bladder was aspirated and sent for culture and sensitivity to Microbiology department. Results: On culture and sensitivity test, 58% have positive growth while 42% has no growth. The most common bacteria isolated was E. coli (23%) followed by Klebsiella spp. (18%), Salmonella spp. (12%) and Shigella spp. (5%) E. coli showed high sensitivity to cefuroxime in 18 (78.3%) cases, whereas, others showed high sensitivity to ciprofloxacin. Discussion: Cholelithiasis is one of the most common diseases of gastrointestinal tract. The biliary tract is usually sterile; however, if cholelithiasis occurs, different microbes might be identified in and/or cultured from the bile or gallbladder wall. The most common bacteria of symptomatic cholelithiasis are E. coli and Klebsiellaspp. followed by Salmonella spp. and Shigella spp. and bile infectionplays a major role in the formation of pigmented gallstones.
Authors and Affiliations
Balaji D Dhaigude, Prithviraj Vivek Patil, Aditya B Patil, Yasaswi K, Parth Patel, Nagendra Yadav, Firoz Alam
Keywords
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