Study of congenital malformations and related maternal and foetal factors: Hospital based study
Journal Title: Medpulse International Journal of Pediatrics - Year 2017, Vol 4, Issue 1
Abstract
Background: Congenital malformation represents defects in morphogenesis during early fetal life. According to the World Health Organization (WHO) document of 1972. Aims and Objectives: To Study of Congenital Malformations and related Maternal and Foetal Factors: Hospital Based Study Methodology : This was a cross sectional study carried out at the Paediatric department of the tertiary health care center during one year period from January 2015 to December 2015. All the 5607 newborns at the tertiary health care centre were screened for congenital malformation clinically and history of mothers like Iron Folic acid Consumption, Consanguinity, Maternal age, Fever with Rash, TORCH infection, Exposure to Smoking, Family history were asked. Result: The incidence of malformation was highest in the Age group >31 i.e. 4.26%and above age group followed by 15-20 1.21%; 26-30-0.81%; 21-25-0.43%and overall the incidence was observed to be 1.30%.The majority of the Associated Maternal Factors found were Age more than 31 Yrs. -53.42%; Inadequate IFA Supplementation -34.24%; H/o Fever with Rash -26.02%;H/o TORCH infection -20.54% H/o Exposure to Smoking -17.80%;Family history -16.43%;Consanguineous marriage -13.69%. The fetal factors associated with the Malformations were Male gender i.e. 63.01% followed by Low birth weight 61.64% ; Twins -20.54%; Birth order >4 -19.17%. Conclusion: In our study we have observed Maternal Factors associated were Age more than 31 Yrs. Inadequate IFA Supplementation; H/o Fever with Rash ;H/o TORCH infection-;H/o Exposure to Smoking; Family history ;Consanguineous marriage; The fetal factors associated with the Malformations were Male gender i.e. 63.01% followed by Low birth weight; Twins ; Birth order >4.
Authors and Affiliations
Bhushan A Miraje, Amar V Naik, Uday A Miraje, Meghana G Kamble, Snehal A Harne
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