Evaluation of efficacy of intravenous magnesium sulphate in general anaesthesia cases for post operative analgesia
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 3, Issue 1
Abstract
Background: Surgical procedures are associated with tissue injury and postoperative pain after surgical interventions. Aim: To evaluate the efficacy of intravenous magnesium sulphate on post operative analgesia following surgeries done under general anaesthesia. Objectives: 1. To evaluate post operative pain at different intervals following the use of preoperative and intraoperative intravenous magnesium sulphate 2. To assess the level of sedation in the immediate post operative period. 3. To monitor hemodynamic parameters perioperatively. Material and Methods: This study was done on 60 patients posted for surgery under general anaesthesia, after fulfilling required formalities. 30 mins before induction of anaesthesia, in Group 1, MgSO4 infusion was administered at the rate of 40mg/kg in 100 ml NS IV over 15 mins and same volume of normal saline was administered in group 2. Results: The mean VAS score postoperatively in magnesium group are at 0,1,2,3,4,8,16,24 hours was 1.96±0.66, 1.46±0.50, 1.20±0.48, 1.33±0.47, 1.43±0.62, 3.00±0.45, 1.70±0.53, 0.86±0.34 respectively. The mean VAS score postoperatively in control group at 0,1,2,3,4,8,16,24 hours 2.56±0.56, 1.96±0.41, 1.76±0.56, 1.96±0.41, 2.30±0.53, 4.16±0.69, 2.36±0.61, 2.00±0.26 respectively. The decrease in pain scores in magnesium group was statistically significant (p<0.05). The mean number of rescue analgesics required postoperatively is lesser in magnesium group compared to that in control group. Conclusion: From the present study it is concluded that IV administration of MgSO4. useful as adjuvant preemptive analgesic, significantly reduces postoperative pain and analgesics requirement..
Authors and Affiliations
Sudeep Sudeep, N Gopal Reddy
Keywords
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