RECENT TRENDS IN POLYMER USE IN BIOADHESIVE DRUG DELIVERY SYSTEM
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Bioadhesion can be defined as the process by which a natural or a synthetic polymer can adhere to a biological substrate. When the biological substrate is a mucosal layer then the phenomena is known as mucoadhesion. The substrate possessing bioadhesive property can help in devising a delivery system capable of delivering a bioactive agent for a prolonged period of time at a specific delivery site. The current review provides a good insight on mucoadhesive polymers, the phenomenon of mucoadhesion and the factors which have the ability to affect the mucoadhesive properties of a polymer. The drugs which have local action or those which have maximum absorption in gastrointestinal tract require increased duration of stay in GIT. Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic activity.
Authors and Affiliations
Nalla Chanda, Thirupathi Reddy A, B Appanna, Ch Papinaidu, D Suvarchala
Keywords
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