DRY EMULSION: A PROMISING DOSAGE FORM TO DELIVER LIPOPHILIC DRUG MOLECULES WITH IMPROVED STABILITY AND EFFECTIVENESS
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Liquid emulsions have distinct advantages over the other oral dosage forms by improving the bio availability and by reducing the side effects, but the number of emulsion formulations currently in use are few compared with other oral dosage forms due to lack of physical - chemical and compliance problems. To overcome these problems dry emulsions are prepared. Dry emulsions are prepared by drying liquid o/w emulsions containing a solid carrier in the aqueous phase. The solid carrier provides the dry emulsions with bulk and mass. Dry emulsions are lipid based powder formulations from which an O/W emulsion can be reconstituted in-vivo or in-vitro. Dry emulsions can be prepared by spray drying, lyophilization and rotary evaporation. Unfortunately the dry emulsions were cohesive powders. The cohesiveness was reduced by addition of sucrose.
Authors and Affiliations
Haritha M, Priyanka M, Abeda Aqther, Neeharika R, Pragati Kumar
Keywords
Related Articles
- EP ID EP33012
- DOI -
- Views 403
- Downloads 0
Stem cell banking: an update on current scenario
The emerging medical science coupled with biotechnological innovations is paving way for an exciting science – stem cell research. The researchers in the area of stem cell banking are exploiting the factual impending m...
Development of RP-HPLC method for the estimation of Oseltamivir in pharmaceutical dosage form
A rapid and precise Reverse Phase High Performance Liquid Chromatographic method has been developed for the validated of Oseltamivir, in its pure form as well as in tablet dosage form. Chromatography was carried out on...
Antimicrobial activity of Vitex leucoxylon, Vitex negundo and Vitex trifolia
In the present study, an attempt was made to investigate the anti-bacterial activity of Vitex leuocoxylon, Vitex negundo and Vitex trifolia. The crude drug powder extracts of the leaves of the above plants were taken f...
Evaluation of in-vitro anthelminthic activity of leaf and bark aqueous extracts of Santalum album linn
Santalum album Linn is the most significant genus in the family Santalaceae, which is commonly known as Sri gandham in India. This study evaluates anthelmintic activity of Aqueous leaf and bark extracts of Santalum alb...
Formulation and evaluation of Escitalopram fast dissolving tablets by direct compression method
The present study is an attempt to select the best possible diluent, disintegrant combination to formulate rapidly disintegrating tablets of Escitalopram which disintegrates in matter of seconds in the oral cavity, the...