Vasoconstrictor for Local Anesthetics

Vasoconstrictor for Local Anesthetics


  • Journal title: Dental Research and Management
  • ISSN: 2572-6978 (print)
  • Publisher: Edelweiss Publications Inc
  • Country of publisher: united states
  • Date added to EuroPub: 2019/Sep/29

Subject and more

  • LCC Subject Category:
  • Publisher's keywords: Local anesthetics.Vasoconstriction.Adrenaline
  • Language of fulltext:
  • Full-text formats available: PDF


    Kentaro Ouchi



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Dental local anesthetics contain vasoconstrictors, such as adrenaline and felypressin, to enhance the anesthetic effects and reduce bleeding in the surgical field. Adrenaline has been used for long periods of time as an additive to local anesthetics. With a typical dose range of 10 - 12.5 μg /mL, adrenaline is believed to prolong duration by its vasoconstrictive properties that prevent systemic reabsorption of local anesthetics. Several reports have warned against the use of dental local anesthetics containing adrenaline in patients with cardiovascular diseases.

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