Synthesis and Antimicrobial evaluation of Azole Based (p-nitro Benzoic Acid) derivatives
Journal Title: Asian Pacific Journal of Health Sciences - Year 2018, Vol 5, Issue 4
Abstract
This study includes the Synthesis of Azoles Based p-nitro Benzoic Acid Derivative. The compounds were prepared by reaction of p-nitro Benzoic Acid with thiosemicarbazide in the presence of Phosphorus oxychloride to yield 1, 3, 4-thiadiazole nucleus. Further this thiadiazole was treated with different aromatic aldehydes in presence of methanol to yield corresponding Schiff’s bases. All the Schiff’s bases thus obtained were reacted with Thioglycolic acid to yield the title compounds. Synthesized derivatives were characterized by IR, H1NMR and screened for their antibacterial (S. aureus, B. subtilis, E. coli, and P. aerugiosa) and antifungal activity (A. Niger and C. albicans).
Authors and Affiliations
Omprakash Sharma
Attenuation of pressor response and dose sparing effect on opioids with the use of dexmedetomidine in spine surgeries
Background: The pressor response, which is part of a huge spectrum of stress response, results from the increase in sympathetic and sympathoadrenal activity, as evidenced by increased plasma catecholamines concentrations...
Medico-social aspects of burn injuries
Background: Globally approximately 2.5 lakh deaths occur every year, with majority of cases from low and middle socioeconomic strata. The epidemiological characteristics of burn may vary widely throughout the world. This...
A Review on Diabetes Mellitus: Current Update on Management and Treatment
Diabetes mellitus (DM), or simply diabetes, is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin...
A report on the quality control parameters of Cressa cretica Linn., Convolvulaceae
Introduction: The present study was aimed at pharmacognostical, phytochemical, and pharmacological evaluation of Cressa cretica Linn., (fruit) family - Convolvulaceae. Materials and Methods: Pharmacognostical investigati...
Association of Depression, Anxiety and Stress with Cognitive functions in female dental students
Background: Professional courses in medical education are highly stressful and students must be aware of the stress and the coping methods in the beginning of the course itself. Excessive, ill managed stress leads to dep...