Role of Procalcitonin as diagnostic marker in neonatal sepsis and its correlation with clinical, biochemical and haematological profile
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 12
Abstract
Neonatal sepsis is the most common cause of morbidity and mortality in neonatal period particularly in the developing countries. Early diagnosis and treatment of sepsis is essential since a delay in treatment can lead to neonatal death. Different investigative techniques are assessed for usefulness, either singly or in combination, for the early detection of neonatal sepsis. The results of blood culture may be negative despite presence of bacterial infection. Therefore, early diagnosis is difficult, despite advanced bacteriological techniques. Inflammatory markers can also be used for early diagnosis such as C-reactive protein but it does not reliably differentiate between systemic inflammatory response and sepsis. Therefore, there is a need to identify a biomarker by which an infected neonate can be identified rapidly before the onset of life threatening symptoms and for the promt institution of anti-microbial therapy, which improves outcomes. Assessment of Procalcitonin (PCT) in the serum may help in the rapid and accurate diagnosis of sepsis as it is a reliable and specific biomarker.
Authors and Affiliations
Utkarshni, Jaspreet Singh, Surinder Paul Kanwardeep Singh, Dr. N. S. Neki
Keywords
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- EP ID EP548956
- DOI 10.22192/ijcrms.2018.04.12.004
- Views 228
- Downloads 0
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