The Effect of Saffron and Purslane Hydroalchoholic Extracts on CKS and LDH Levels in Rat Serum
Journal Title: International Research Journal of Applied and Basic Sciences - Year 2016, Vol 10, Issue 5
Abstract
It is estimated that there are 500,000 species of plants on Earth. Relatively small percentages of these are used as foods by both humans and other animal species.Medicinal plantsusedin traditional medicineto treatvarious diseasesare growing in our country, butthe effects ofbiological active compoundsof these plantsarestillunknown on human health. Crocus sativusand Portulaca Oleracea are widely used inIran as herbal medicine. This study was performed to evaluate the effects of ethanol extraction of Crocus sativusand Portulaca Oleracea on the LDH and CK. Fifty Sprague- Dawley rats were allocated to five equal groups. The animals in groups 1 and 2 received Crocus sativusextract and the rats of thethird and fourth group received Portulaca Oleracea extract. The rats in group 5, as the untreated group received ordinary diet.The results of this study indicate that Portulaca Oleracea extract was able to increase the LDH level in group 3 and 4 compared with the control group. The highest increase inthe LDH level was observedinthe group 4 that receivingthe lowerdose ofthe Portulaca Oleracea extract. This increasewas significantwhen compared tothe group 2The increase ofserumLDHlevelscouldbeindicative ofachronic necrosis in theliver. The highestlevelof serumCKwas observedinratsreceivingthe highdose of Crocus sativusand low dose of Portulaca Oleracea, but exhibited no statically significant difference compared with control (P>0.05).
Authors and Affiliations
Kaveh Berenjian| Student Research Committee, Kermanshah University Medical Sciences, Kermanshah, Iran, email: Kaveh.berenjian@gmail.com, Mahin Hossini| Educational Technology A.M, Kermanshah, Iran
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