A COMPARATIVE STUDY OF INTRATHECAL DEXMEDETOMIDINE AND FENTANYL AS ADJUVANTS TO BUPIVACAINE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 51
Abstract
BACKGROUND Uncontrolled postoperative pain may produce a range of detrimental acute and chronic effects. Spinal anaesthesia provided by Bupivacaine may be too short for providing postoperative analgesia. This study is conducted to evaluate the efficiency of intrathecal Fentanyl and intrathecal Dexmedetomidine as an adjuvant to hyperbaric Bupivacaine with regards to onset and duration of sensory and motor blockade as well as postoperative analgesia and adverse effects. The aim of this study is to study the duration of sensory and motor block of dexmedetomidine and fentanyl. MATERIALS AND METHODS Hundred patients aged 18 - 55 years were randomly divided into two groups by a computer program; each group consisting of 50 patients of either sex belonging to ASA Class 1 and 2, posted for elective lower abdominal surgeries were given spinal anaesthesia using Bupivacaine 0.5% heavy 2.5 mL with either Fentanyl 25 ug Group F or preservative-free Dexmedetomidine 5 ug Group D. Assessment of sensory and motor blockade were done at the end of each minute till the maximum level achieved. Measurement of blood pressure, pulse rate, respiratory rate and arterial oxygen saturation were obtained. Postoperatively, patients were observed for the duration of analgesia, time taken for complete regression of sensory blockade and time taken for complete recovery of motor power. RESULTS Our results showed a statistically highly significant prolongation of sensory and motor blockade, time taken for sensory regression by two segments and postoperative analgesia in Dexmedetomidine group compared to Fentanyl group. Incidence of pruritus is significantly high in fentanyl group. CONCLUSION Dexmedetomidine in the dose of 5 ug significantly prolongs the duration of sensory and motor blockade, time taken for sensory regression by two segments and duration of postoperative analgesia than Fentanyl 25 ug when added to Bupivacaine 0.5% heavy.
Authors and Affiliations
Dadichiluka Veeragouri Sankararao
Keywords
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- EP ID EP220240
- DOI 10.18410/jebmh/2017/614
- Views 118
- Downloads 0
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