A COMPARATIVE STUDY OF SMALL DOSE OF KETAMINE, MIDAZOLAM AND PROPOFOL AS COINDUCTION AGENT TO PROPOFOL
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 64
Abstract
BACKGROUND The technique of “coinduction”, i.e. use of a small dose of sedative agent or another anaesthetic agent reduces the dose requirement as well as adverse effects of the main inducing agent. Ketamine, midazolam and propofol have been used as coinduction agents with propofol. MATERIALS AND METHODS This prospective, randomised clinical study compared to three methods of coinduction. One group received ketamine, one group received midazolam and one group received propofol as coinducing agent with propofol. RESULTS The study showed that the group receiving ketamine as coinduction agent required least amount of propofol for induction and was also associated with lesser side effects. CONCLUSION Use of ketamine as coinduction agent leads to maximum reduction of induction dose of propofol and also lesser side effects as compared to propofol and midazolam.
Authors and Affiliations
Abhimanyu Kalita, Abu Lais Mustaq Ahmed
Keywords
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- EP ID EP228471
- DOI 10.18410/jebmh/2017/763
- Views 52
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