“A hospital based study on the value of hemoglobinuria in the diagnosis and outcome in cases of complicated malaria”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 4
Abstract
1. Introduction: Malaria is a global health problem with over 40% of the world’s population i.e. more than 3000 million people exposed to varying degrees of malaria risk in some 108 countries. The intravacualr haemolysis can be due to non-immune destruction of parasitized red blood cells in case of high parasitemia or due to immune mediated destruction of parasitized as well as non-parasitized red cells. 2. Material and Method: The present study “A hospital based study on the value of hemoglobinuria in the diagnosis and outcome in cases of complicated malaria” was carried out in the patient admitted in the Department of Medicine of Rajendra Institute of Medical Sciences, Ranchi, with diagnosis of P. falciparum malaria suggestive of complicated (severe) form of falciparum malaria according to WHO 2000 criteria. 3. Results: Parasite density ranged from 3-18%, and high parasite density > 10% was associated with increased morbidity and mortality in hemoglobinuria patients compared to patients without hemoglobinuria. Overall mortality in complicated malaria was 275%. Out of these deaths, 41.17% was seen in hemoglobinuria patients and 23.80% in patients without hemoglobinuria. 4. Conclusion: There is definite correlation between parasitemia and hemoglobinuria.early detection can leads to decreased mortality.
Authors and Affiliations
Dr. Pradeep Prasad, Dr. Sanjay Kumar
Keywords
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- DOI 10.9790/0853-1704021924.
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