A prospective observational study to measure drug compliance in epilepsy patients attending Chakrapani neuro care hospital
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 4
Abstract
Purpose: Epilepsy may promote limitations and restrain activities, interfering with the occupational ability, professional goals and social integration of patients. It increases morbidity and symptomatic epilepsy reduces life expectancy by 18 years at maximum. It continues to be a highly stigmatized and disabling chronic condition requiring a lifelong process of adherence to the prescriber’s instructions and drug regimens. But many people cannot follow the order and seizure can occur from anti-epileptic drug withdrawal. So, measuring and monitoring of drug compliance is essential. Methods: Totally 75 epilepsy patients were assessed, among which 60 patients who met the inclusion criteria were recruited into the study and were interviewed by using a structured questionnaire. The survey approach was used in the study. The study period was 6 months. Results: Majority of patient’s age of onset of epilepsy was above 18 years. Majority of the patients have been suffering from epilepsy from past 1 year to 10 years. Among 60 patients, there were 28 (47%) patients with GTCS, 22 (36%) patients with CPS. Majority (63%) of the sample were compliant to the medication. According to the study, 27% of the sample stated cost factor as the reason for non-compliance. Among 29 (48%) patients who experienced side effects, majority (43%) suffered from drowsiness. Conclusion: There was a significant relationship between history of non-compliance [P-value 0.95 > 0.05 level of confidence] and present state of noncompliance. Other major factors influencing the drug compliance were found to be Education (P=0.5), Duration of illness (P=0.5), Side effects (P=0.25), Expenditure (P=0.5), Type of Therapy (P=0.75) and Frequency of Medication (P=0.25).
Authors and Affiliations
Padala kalyani, Shahnaz, K. Suvarna Laxmi, A. Kishore babu, A. Srinivasa rao, B. Chakrapani
Keywords
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