A prospective, randomized study to compare epidural bupivacaine 0.125% and ropivacaine 0.2% with fentanyl combination for post-operative analgesia in lower abdominal and lower limb surgeries
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 4, Issue 2
Abstract
Background: A combination of local anesthetic agent with opioids like fentanyl administered in the epidural space provides effective postoperative analgesia in a lower dose to achieve the desired analgesic effect. Aim: To compare epidural bupivacaine 0.125% and ropivacaine 0.2% with fentanyl combination for lower abdominal and lower limb surgeries. Material and Methods: A total of 72 patients scheduled to undergo elective lower limb or lower abdominal surgery were randomized into two groups. Group 1 received 0.125% Bupivacaine with Fentanyl 2µg/ml, and Group 2 received 0.2% Ropivacaine with Fentanyl 2µg/ml each at 6ml/h via piston driven syringe pump over a period of 24 hours. Results: The VAS at rest and movement/cough and the NRS was clinically higher for bupivacaine group, but the difference was statistically not significant (p>0.05). Clinically, more doses of rescue analgesic were required in bupivacaine group, but the difference was not significant statistically (p>0.05). The number of patients having significant motor blockade was higher in bupivacaine group but the statistically the difference was significant only at ‘0’ hour (p<0.05). Conclusion: Both the groups were clinically comparable. Patient satisfaction was probably better in ropivacaine group compared to bupivacaine group. Requirement of rescue analgesia was more in bupivacaine group
Authors and Affiliations
Gayathri Devi B U, Attarde Viren Bhaskar
Keywords
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