A STUDY OF PREDICTABILITY OF BLEEDING RISK IN PEDIATRIC DENGUE INFECTION WITH SIMPLE HAEMATOLOGICAL TESTS
Journal Title: Mintage journal of pharmaceutical and medical sciences - Year 2016, Vol 5, Issue 8
Abstract
Background and aim: Predicting of bleeding risk in dengue infection with feasible means continues to be important concern. This study evaluates usefulness of basic hematological tests in this respect. Method: This is cross sectional study in pediatric dengue patients categorized as not bleeding; having petechial bleeds and having mucosal bleeds. At the highest measured packed cell volume (PCV) in the patients during hospitalization, bleeding status was noted, simultaneously with platelet and leukocyte counts. Patients were segregated around medians of these parameters to assess relation to bleeding status. Odds ratios were calculated to indicate bleeding risk. Results: Of duely investigated 95 cases, 68 had bleeds, 40 with petechie and 28 with mucosal spots. Median highest PCV was 37.1%, and median platelet and leukocyte counts were respectively 52000/micro litre and 3400/micro litre. Odds ratio of bleeding risk above median PCV values was 2.16 times, that for petechie 2.07 and for mucosal bleeds 2.27 times. Below median platelet counts yielded bleeding risk odds ratios 2.19 times overall, 1.9 for petechie and 3.06 for mucosal bleeds. Leukocyte counts did not appear to be consequential. Conclusion: Basic laboratory evaluations of PCV and platelet count are found useful to predicting bleeding risk in pediatric dengue infection.
Authors and Affiliations
abha pandit, anita mehta
Keywords
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