A study of renal manifestations in hypothyroid patients found during pre anesthetic check up
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 3, Issue 2
Abstract
Background: Thyroid hormone influences renal development, kidney structure, renal heamodynamics, GFR, the functions of many transport system along nephron, sodium and water homeostasis Disorder of thyroid function can result from any abnormality that leads to insufficient synthesis of thyroid hormone. The most common primary hypothyroidism is linked to immune mediated glomerular injury and alteration in the production of thyroid hormone. The presence of hypometabolic state thus necessitates careful perioperative renal, cardiovascular monitoring and judicious use of anaesthetic drugs. Aim: The present study was aimed to analyse renal parameters – blood urea, serum and urinary creatinine, serum and urinary electrolytes in patients with history of hypothyroidism posted for elective surgery during the year 2016 at Deccan College of Medical Sciences. Material and Method: The following biochemical parameters derived were estimated glomerular filtration rate (eGFR) and fractional excretion of sodium (FeNa). 50 people were taken as controls that had no medical illness and 50 cases of incidental subclinical hypothyroidism were taken as case study group. Mean and Standard deviation was assessed and p value ≤0.05 was considered significant. Result: The mean and SD of blood urea (mg/dl) in controls is 28.2±4.75 as compared to 27.29±8.1 in cases. The P value is not significant. The mean and SD of serum creatinine (mg/dl) in controls was 0.7±0.15 as compared to 1.10±0.24 in cases. The P value was <0.01 which is significant. The mean and SD of electrolytes sodium, potassium and chlorides in controls were 140.4±2.15, 4.06±0.25 and 98.3±2.25 as compared to case study group of 147.93±6.98, 4.15±0.42 and 107.81± 10.35 The P value of serum sodium and chloride is <0.01 which is significant. The p value of potassium is not significant
Authors and Affiliations
Mahmood Mirza, Khaja Ali Hassan, Jaweed Zaheer Siddique, Wajid Ali Khan, Mohammad Aejazul Haq
Keywords
Related Articles
- EP ID EP260990
- DOI -
- Views 158
- Downloads 0
Role of serum zinc level in simple febrile seizures: A hospital based study from rural area of Maharashtra
Introduction: Febrile Convulsion is the most common type of seizure in children between 5 months to 6 years of age. Low levels of serum zinc suggestive of increased incidence of simple febrile seizure. Aim: The aim of th...
Study of spinal anaesthesia in paediatric age group in rural set-up
Background: The commonly adopted method of anaesthesia in children is general anaesthesia (GA) as per the traditional standards. But, in rural set up, where there is lack of finance, high tech monitoring equipment, man p...
A comparative study between ketamine nebulization and betamethasone gel applied over the endotracheal tube cuff for reduction of post-operative sore throat
Background: Endotracheal intubation is necessary in general anesthesia (GA) to control respiration and to protect airway. Larynx and trachea are the most common sites of injury during intubation and usually manifested as...
Comparative study of the analgesic efficacy of rectal tramadol versus intravenous tramadol for inguinal hernia repair surgery
Background: Pain in the perioperative setting plays a significant role in delaying an otherwise successful recovery. Tramadol is an atypical opioid having central as well as peripheral analgesic action. We compare the ef...
Comparison of I-gel versus proseal laryngeal mask airway (PLMA) for elective surgical elective surgical procedures
Background:Securing airway of patient during surgery is one of the most important responsibility of anesthesiologist.Though Endotracheal Tube is gold standard for securing airway during general anesthesia, various suprag...