A study on bacterial and fungal infections in renal transplant recipients
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 4
Abstract
The two major hurdles to successful renal transplantation are rejection and infection. Infection is the leading cause of morbidity and mortality in renal transplant recipients, with more than 80% suffering at least one episode of infection within a year. Our aim was to determine the prevalence of bacterial and fungal infections among transplant infections and their antimicrobial susceptibility pattern in renal transplant recipients. We conducted a retrospective study in 100 consecutive renal transplant recipients admitted with bacterial and fungal infections. Among 100 patients, 80 were males .The most common age group affected were 25 -35 years and the mean age was 30.5 yrs. About 72 patients had live related renal transplantation (LRRT) and 28 had deceased donor renal transplantation (DDRT). The most common symptoms were fever and burning micturition. On the whole, 74% of the transplant recipients had culture positivity and 26% were negative. Bacterial infections were in 90 and fungal in 10.Klebsiella and candida were the commonest species isolated respectively. Urinary tract infection (UTI) was the commonest infection followed by respiratory infection (RTI),skin and soft tissue infection (SSTI) and blood stream infection (BSI) /sepsis. The most common resistance pattern observed was the production of Extended Spectrum Beta Lactamases and Imipenem resistance was found to be minimal.To conclude benign UTI should not be neglected as it may progress to sepsis and graft dysfunction. Renal transplant recipients should be followed up and monitored regularly since they have increased morbidity and mortality rate due to infections.
Authors and Affiliations
Kandasamy Anuradha
Keywords
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