Anterior segment and corneal biomechanics of achondroplasia patients
Journal Title: Ege Tıp Dergisi - Year 2018, Vol 57, Issue 2
Abstract
Herein the anterior segment findings with Pentacam and corneal biomechanics with Ocular Response Analyser of 4 genetically proven cases of achondroplasia are reported. Four patients with heterozygous gain of function p.G380R mutation in fibroblast growth factor receptor 3 (FGFR3) gene were evaluated. Central corneal thickness was higher than normal in both eyes of one patient, and corneal hysteresis and corneal resistance factor was lower in three eyes of two patients with accompanying high intraocular pressure readings. As a result, the affection of FGFR3 in achondroplasia patients might cause changes in central corneal thickness, corneal hysteresis and corneal resistance factor.
Authors and Affiliations
Melis Palamar, Huseyin Onay, Tahir Atik, Suzan Güven Yilmaz, Ferda Ozkınay
Keywords
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