Clinical Profile of Mucormycosis: A Descriptive analyses
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 6
Abstract
Background: Mucormycosis is a relatively rare opportunistic fungal infection. It is one of the devastating infections of immunocompromised host. Though several studies were done in India and elsewhere on Mucormycosis, it has not been extensively studied of late. Objectives: The objective of the study is to study the clinical profile of Mucormycosis in the medical college at Moradabad, Uttar Pradesh. Methods: Our series compromised of 14 cases seen over a period of 3 years. Detailed history, clinical examination, laboratory investigations were carried out in all the cases. Results: The study group consisted of 10 males and 4 females aged 20 – 70 years (mean 50 years). Most of the patients in the study group had evident blackish nasal eschar and sinus disease. Cultures were positive for Mucorales in 08 cases. 11 patients were treated with amphotericin B in the doses ranging from 0.5 – 1.0 mg/kg up to a total of 2.6 grams, and duration of the treatment varied from 1 – 31 days. Conclusions: Mucormycosis is a rare opportunistic fungal infection with rapidly progressive and fulminant course with often fatal outcome. A strong suspicion, prompt diagnosis with pathological confirmation and aggressive surgical treatment gives a better outcome.
Authors and Affiliations
Ex. Maj. S K Gupta
Keywords
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