ÇÖLYAK HASTALIĞI DİYET UYUMUNDA YENİ BİR BELİRTEÇ: DELTA NÖTROFİL İNDEKS?

Journal Title: Kocatepe Medical Journal - Year 2021, Vol 4, Issue 22

Abstract

OBJECTIVE: Celiac Disease is an enteropathy caused by the consumption of foods containing gluten and characterized by autoimmune events in the small intestine. In our study, we aimed to show the relationship between the activation criteria that increased with dietary incompatibility and the delta neutrophil index in celiac disease. MATERIAL AND METHODS: In this study, between January 2019 and December 2019, 99 children and adolescents (under the age of 18) who were admitted to the Sami Ulus Maternity and Children's Hospital pediatric gastroenterology outpatient clinic and previously diagnosed with celiac disease were included. RESULTS: A total of 99 celiac patients between the ages of 3 - 17, 45 girls (45.5%) and 54 boys (54.5%), were included in the study. There was no significant relationship between Delta Neutrophil Index (DNI) and duration of diagnosis (p = 0.094 r = 0.169)., dTGA (p = 0.256 r = 0.115), dTGG (p = 0.359 r = -0.094) and IgA (p = 0.259 r = 0.115). CONCLUSIONS: Early diagnosis and treatment of celiac disease are very important because after a gluten-free diet, both symptoms regress and the development of more severe celiac-related damage can be prevented. The serological tests used to determine the dietary compliance of the patients during the follow-up were compared with the DNI level, which is one of the routine hemogram parameters used in many inflammatory conditions, but no statistically significant relationship was found. Dietary compliance can be determined by further studies in the follow-up of celiac patients.

Authors and Affiliations

Nilgün EROĞLU, Gülseren ŞAHİN, Ferda ÖZBAY HOŞNUT, Gürses ŞAHİN

Keywords

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  • EP ID EP697193
  • DOI https://doi.org/10.18229/kocatepetip.864099
  • Views 125
  • Downloads 0

How To Cite

Nilgün EROĞLU, Gülseren ŞAHİN, Ferda ÖZBAY HOŞNUT, Gürses ŞAHİN (2021). ÇÖLYAK HASTALIĞI DİYET UYUMUNDA YENİ BİR BELİRTEÇ: DELTA NÖTROFİL İNDEKS?. Kocatepe Medical Journal, 4(22), -. https://europub.co.uk/articles/-A-697193