Control of haemodynamic responses by butorphanol and fentanyl during various surgeries: A comparative study
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 7, Issue 2
Abstract
Background: Butorphanol is a morphinan chemically related to levorphanol and has mixed agonist-antagonist properties. It is more potent and it has advantage of producing less addiction and respiratory depression. Fentanyl is μ, receptor agonist, structurally related to phenylpiperidines having clinical potency ratio 50 – 100 times of morphine. It is more potent. Butorphanol tartarate is a totally synthetic narcotic antagonist analgesic, which does not require opium alkaloids for its synthesis. This drug with its combined antinarcotic and Aim and objective: To compare haemodynamic parameters (pulse, SBP, DBP, MAP, SpO2) during general anaesthesia in patients receieving butorphanol and fentanyl. Methodology: In our study 60 cases were divided randomly into two groups. Group A patients received inj .butorphanol tartarate and Group B patients received inj fentanyl citrate. The complete data was recorded by a single observer regarding haemodynamic parameters (systolic blood pressure, diastolic blood pressure, heart rate etc.) intraoperatively as well as postoperatively. Results and discussion: Haemodynamic parameters remained on higher side for first 5 minutes in those who received fentanyl .After 15 minutes difference in parameters in both groups was statistically non significant
Authors and Affiliations
Parikshit Dinkar Salunkhe, Yogesh Magan Suryavanshi
Keywords
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