Correlations between hemoglobin, serum ferritin, and soluble transferrin receptor levels in children aged 6-59 months
Journal Title: Paediatrica Indonesiana - Year 2014, Vol 54, Issue 2
Abstract
Background Early detection of iron deficiency is important in young children to prevent iron deficiency anemia, which may cause permanent neurocognitive development disorders. Hemoglobin level is an insensitive tool for detecting iron deficiency without anemia, while serum ferritin levels may be influenced by infection and inflammation. However, soluble transferrin receptor (sTfR) is a sensitive marker for detecting iron deficiency, yet not widely used in daily practice.Objective To assess for correlations between hemoglobin, serum ferritin, and soluble transferrin receptor levels in children aged 6-59 months.Methods We performed a cross-sectional study in the Yogyakarta and Bantul Districts involving 85 children aged 6-59 months who visited integrated health posts (posyandu) and who met the inclusion criteria. Subjects were chosen by cluster random sampling. Blood specimens were collected to examine hemoglobin, serum ferritin, and sTfR levels.Results Spearman’s correlation test revealed weak negative correlations between hemoglobin and serum ferritin levels, as well as between hemoglobin and sTfR levels, with coefficient correlations of r = -0.220, (P=0.043) and r = -0.317, (P=0.003), respectively. There was no correlation between serum ferritin and sTfR levels (r = -0.033; P=0.767).Conclusion Hemoglobin levels has weak negative correlations with serum ferritin and sTfR, but serum ferritin does not correlate with sTfR. [Paediatr Indones. 2014;54:122-6.]
Authors and Affiliations
Fajar Tri Kusumastuti, Sutaryo Sutaryo, Sri Mulatsih
Keywords
Related Articles
- EP ID EP458715
- DOI 10.14238/pi54.2.2014.122-6
- Views 66
- Downloads 0
Risk factors for neonatal mortality at Moewardi Hospital, Surakarta
Background Neonatal mortality remains a major concern indeveloping countries. Identifying potential risk factors is importantin order to decrease the neonatal mortality rate. In MoewardiHospital, Surakarta, the risk fact...
Comparing sleep disorders in urban and suburban adolescents
Background Sleep disturbances commonly occur in adolescents. Socioeconomic levels, lifestyle, and urban or suburban environments influence the sleep patterns of adolescents. The modernization process in urban environment...
Risk factors for hearing loss in neonates
Background An estimated 6 of 1,000 children with live births suffer from permanent hearing loss at birth or the neonatal period. At least 90% of cases occur in developing countries. Hearing loss should be diagnosed as ea...
Prognostic factors for success in the Kangaroo Mother Care method for low birth weight babies
Background Low birth weight (LBW) is closely related to neonatal morbidity and mortality. Management of LBW infants in developing countries remains limited, due to the low availability of incubators. The Kangaroo Mother...
Correlation between immunization status and pediatric diphtheria patients outcomes in the Sampang District, 2011-2015
Background The number of diphtheria cases recently increased, such that an outbreak was declared in East Java Province, which includes the Sampang District. Immunization completion status is a determining factor for dipt...