Demographic findings of patients diagnosed with pernio and comparison of their vitamin B12, folate and ferritin levels with a control group
Journal Title: Türkderm - Deri Hastalıkları ve Frengi Arşivi - Year 2019, Vol 53, Issue 3
Abstract
Background and Design: Pernio is an inflammatory disease that occurs in the acral regions of the body after exposure to cold. The study aimed to investigate the demographic findings of patients diagnosed with pernio and to determine the role of vitamin B12, folate and ferritin values in the pathogenesis of pernio. Materials and Methods: This study was conducted in pernio patients diagnosed at the Ağrı State Hospital, Clinic of Dermatology Outpatient Clinic (Ağrı, Turkey) between September 2015 and April 2016. The healthy control group participants were of similar age and gender. Vitamin B12, folate and ferritin level measurements were compared between the groups. Results: The patient and control groups were similar in age and gender. Vitamin B12 and ferritin levels were significantly lower in the patient group (p<0.05). Folate levels did not differ significantly between the groups (p>0.05). Conclusion: According to the data obtained from our study, when the demographic findings of the pernio patients were compared with those in the literature, the results were found to be similar. In the patients with pernio, it is likely that low Vitamin B12 was involved in the pernio etiology via the mechanism of vasoconstriction/vasodilatation.
Authors and Affiliations
Ebru Karagün, Sevim Baysak
Keywords
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