DETECTION OF IgM ANTIBODIES TO LEPTOSPIRA IN HUMAN POPULATION WITH OCCUPATIONAL RISK FACTORS IN VILLAVICENCIO, META.
Journal Title: Revista MVZ Cordoba - Year 2008, Vol 13, Issue 1
Abstract
Objective. To determine the occupational seroprevalence of infection by Leptospira and associate factors in a human population in the municipality of Villavicencio, Meta, Colombia. Materials and methods. A cross-sectional study was applied using occupational population groups selected by convenience. Samples of blood corresponding to 8 risk groups were obtained (n=273) by cubital venipuncture. Information on risk factors was obtained by a standardized interview. IgM antibodies were determined by means of Indirect ELISA. A Chi square test was applied using of SPSS 11.0 for Windows. Results. General seroprevalence was 19%. For occupational groups values were: 7% for slaughterhouse workers, 17% for veterinarians and small animal clinic assistants, 17% for students in their last year of veterinary Medicine and Zootechnical science, 21% for people milking cows , 23% for rice field workers, 35% for those working on pig-farms and 48% for fish farm workers. Three factors were found to be associated: rural social level (p=0.0005; ICCR 1.50 to 3.83), having a pet dog (p=0.046; ICCR 1.03 at 3.26) and coming into contact with rodents in the workplace (p=0.046; ICCR 1.03 to 3.26). Conclusions. A high seroprevalence for Leptospira spp was found in at-risk groups, with people working on pig-farms and fish-farms being most affected. The occupational character of the infection is recognized once more, and the possible association with lack of hygiene measures and labor protection.
Authors and Affiliations
Luz Díaz P,MVZ| 1Universidad de los Llanos., Irma Zapata,MVZ| 1Universidad de los Llanos., Agustín Góngora O,Ph. D*| Universidad de los Llanos, Grupo de Investigación en Reproducción y Genética Animal (GIRGA).Correspondencia: agongora@unillanos.edu.co, Jorge Parra A,M. Sc| Investigador Asociado Corpoica. La Libertad Villavicencio, Colombia., Luz Aponte G,Esp| Universidad de los Llanos, Escuela de Enfermería, Grupo de Investigación Salud en el Trópico., Luz Gómez L,Esp| Universidad de los Llanos, Escuela de MVZ. Villavicencio, Colombia.
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