DIFFUSION WEIGHTED IMAGING OF SOFT TISSUE MASSES: CAN APPARENT DIFFUSION COEFFICIENT MEASUREMENT DIFFERENTIATE BETWEEN MALIGNANT AND BENIGN LESIONS ?
Journal Title: Kocatepe Medical Journal - Year 2023, Vol 24, Issue 4
Abstract
OBJECTIVE: To investigate the efficacy of apparent diffusion coefficient (ADC) mapping obtained using the diffusion-weighted imaging (DWI) method in the differentiation of benign and malignant lesions of soft tissue tumors and to establish a quantitative cut-off value for ADC to be used in the differentiation of these lesions. MATERIAL AND METHODS: This retrospective study included a total of 34 patients who underwent DWI due to soft tissue masses and had available histopathological results. According to the pathological results; patients were categorized as having benign and malignant lesions. Measurements were performed using the free hand-drawn region of interest technique. It was investigated whether there was any difference in the evaluated parameters (size, age, gender, and minimum, mean and maximum ADC values). The cut-off value for the parameters evaluated in DWI was determined by the Receiver Operating Characteristic (ROC) analysis. RESULTS: The mean minimum ADC value was 1,28×10-³mm²/s in benign soft tissue masses and 1,00×10-³mm²/s in malignant soft tissue masses. Minimum ADC values differ statistically between the two groups. (p=0,007). A cut-off value of ≤1,01×10-³mm²/s for the minimum ADC allowed for the characterization of soft tissue masses at 78,95% sensitivity and 73,33% specificity. However, the mean and maximum ADC values were not statistically significantly different between the two groups. (p=0,319 and 0,960, respectively). CONCLUSIONS: DWI is an effective method in the evaluation of soft tissue masses in the differentiation of benign and malignant, and taking the cut-off value as ≤1,01×10-³mm²/s in the calculation of minimum ADC will increase the clinical usefulness.
Authors and Affiliations
Mehmet OĞUZMAN Cüneyt ÇALIŞIR Ulukan İNAN
Keywords
Related Articles
- EP ID EP722687
- DOI https://doi.org/10.18229/kocatepetip.1122866
- Views 47
- Downloads 0
A CASE OF SPONDYLODISCITIS DUE TO CORYNEBACTERIUM TUBERCULOSTEARICUM
Although Corynebacterium species are often isolated from clinical specimens, it can be difficult to distinguish between infection and colonization due to their presence in normal skin flora. When the literature is evalua...
THE EVALUATION OF DEPRESSION AND SOCIAL ANXIETY AMONG CHILDREN WITH CELIAC DISEASE
OBJECTIVE: Depression and anxiety levels adult patients with celiac disease (CD) have been investigated and conflicting results have been reported. However, there are limited studies on the association of CD with depre...
PATIENTS NON-COVID-19 DIAGNOSIS IN PANDEMIC CLINICS: THREE CASE REPORTS
With the pandemic process, the frequency of clinicians' referrals for thoracic imaging has increased. In this article, three cases diagnosed other than COVID-19 in pandemic clinics are presented. A 33-years-old male admi...
PREOPERATIVE EVALUATION OF LIVING DONOR KIDNEY VARIATIONS WITH MULTIDETECTOR COMPUTED TOMOGRAPHY AND COMPARISON OF RESULTS WITH INTRAOPERATIVE FINDINGS
OBJECTIVE: The aim of this study was to evaluate the renal vascular and collecting system variations in living kidney donors using multidetector computed tomography (MDCT) and to compare the data with the findings detect...
CHOROIDAL THICKNESS IN PATIENTS OF MATURITY ONSET DIABETES OF THE YOUNG WITH POSITIVE GLUCOKINASE GENE MUTATION
OBJECTIVE: The aim of this study was to compare the choroi-dal thickness (CT) of patients diagnosed with maturity onset di-abetes of young (MODY) with positive glucokinase (GCK) gene mutation with healthy individuals. M...