TGF-β regulates invasive behavior of human pancreatic cancer cells by controlling Smad expression

Introduction: To investigate the role of Smads in tumor cell activation, we examined changes in Smad expression as well as changes in proliferative and invasive behaviors in transforming growth factor-β (TGF-β) – stimula...

The estimation of erythropoietin levels in the blood serum and cystic fluid in patients with solitary renal cysts

Introduction: The role of erythropoietin (EPO) in patients with renal cysts remains unclear. Some authors suggest that EPO may be produced in renal cysts (RC). The aim of the study was to answer the question why concent...

Maternal palmvitee administration reduced plasma total bilirubin and uridine diphosphate glucuronyltransferase activity in hyperbilirubinaemic rat neonates

Does early insulin treatment decrease the risk of microangiopathy in non-obese adults with diabetes?

Introduction: In the clinical practice classification of diabetes type in adult patients is often difficult. In non-obese adults distinguishing between Latent Autoimmune Diabetes in the Adult and type 2 diabetes leads to...

The leukemogenic role of (iASPP) in acute leukemia

Introduction: The ASPP family (apoptosis – stimulating proteins of p53) comprises three proteins, ASPP1, ASPP2 and iASPP, that interact with and modulate the behavior of p53. ASPP1 and ASPP2 enhance the ability of p53 to...