Epidermodysplasia Verruciformis in A HIV Patient –A Rare Case Report
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Epidermodysplasia Verruciformis (EDV), is a rare autosomal recessive genodermatosis with cases linked to chromosome X, and attributed to infection by specific types of Human Papilloma Virus (HPV) in immunologically deficient individual. There is an increased prevalence and decreased clearance of HPV infections in HIV infected patients. Malignant change occurs in about 20-30% cases mainly on sun exposed areas. Clinically presents as plane warts, reddish verrucous plaques or pityriasis versicolor like lesions mostly on sun exposed sites. There is no effective treatment. We present an 19 years old married HIV positive female case with asympotamatic hypopigmented macules and flat topped papules on face, neck, trunk and upper extremities since 4months. Punch biopsy of lesion on forearm showed epidermal acanthosis, hypergranulosis, hyperkeratosis, mild papillomatosis, enlarged, and altered keratinocytes with purple-blue cytoplasm suggestive of EDV. After clinico-histopathological correlation, the diagnosis of HIV associated EDV was made. We kept her on sunscreen with SPF 30.
Authors and Affiliations
Doogana Vishali, V. Nivedita Devi
Keywords
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- EP ID EP467034
- DOI 10.9790/0853-1802060507.
- Views 52
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