Evaluation Antioxidant and Antibacterial Activities of n-Butanol Fraction of Conocarpus Erectus L. Leaves Extract

Abstract

N-butanol extract of Conocarpus erectus L. leaves was studied for antioxidant and antibacterial activities. In vitro systems for example, 1, 1- diphenyl-2 picrylhydrazyl (DPPH) radical, and antioxidant capacity (Ferric Reducing Antioxidant Power, FRAP assay). The antibacterial activity was determined using the hole-in-plate agar diffusion. The extract scavenged DPPH radicals comparable with ascorbic acid and butyl hydroxytoluene (BHT). The n-butanol extract of Conocarpus erectus L. leaves showed high free radical scavenging activity toward DPPH radical between (29.87-79.33). The n-butanol extract had radical scavenging activity less than the Ascorbic acid (34.61-80.76) and butyl hydroxytoluene (BHT) (33.33-66.66). The results indicated the antioxidant capacity of butanol extract had a significantly (0.50-1.11nm) much higher than ascorbic acid (0.5-0.86nm ) and butyl hydroxytoluene (BHT) (0.30-0.76nm). Antibacterial activity was found to be present in nbutanol extract of Conocarpus erectus L. leaves being highest in Straptococcus (22mm). Zones of inhibition for E.coli, Staph. aureus and Enterobacter were 21, 20 and 19 respectively. Results show plants to possess antibacterial activity.

Authors and Affiliations

Rawa A. Hussein

Keywords

Related Articles

Ayurvedic remedies for healing of wounds: A Review

Healing of wounds, whether from accidental injury or surgical invention, involves the activity of an intricate network of blood cells, tissue types, cytokines, and growth factor. The traditional Indian medicine - Ayurv...

Pattern of opportunistic infection among HIV/AIDS patients visiting a rural teaching hospital of Maharashtra

Introduction: The most advanced stage of HIV infectio is Acquired Immunodeficiency Syndrom (AIDS); defined by the occurrence of any of more than 20 opportunistic infections or related cancers. HIV/AIDS remains one...

Synthesis and Antimicrobial Activity of 5-{4'-[(4"-aryl)- -3"-cyano 2"-ethoxy pyridine-6"- yl] phenyl carbamido}-dibenz [b,f] azepines derivatives

The titled compounds (4a-4k) have been synthesized by the condensation of 5-{4'-[(3"-aryl)-2"- Propene-1"-one]-Phenyl carbamido}-dibenz [b,f] azepines with malononitrile and Sodium ethoxide. The biological activities o...

Plants used by the local inhabitant of bhabar tract for hair related problems

Hair related problems are really an important issue any one can face in life. In Today’s life hair related problems are very common due to many reasons like- illness, tension, hormone imbalance, polluted water and air, h...

Synthesis Design of an Anti-Obesity Agent ‘Sibutramine’: A Reatrosynthetic Approach

Organic synthesis plays the central role in the process of drug design and development. Retrosynthetic analysis represents a very powerful tool for designing convergent and economical synthetic routes of targeted drugs...

Download PDF file
  • EP ID EP31531
  • DOI -
  • Views 311
  • Downloads 1

How To Cite

Rawa A. Hussein (2016). Evaluation Antioxidant and Antibacterial Activities of n-Butanol Fraction of Conocarpus Erectus L. Leaves Extract. International Journal of Pharmaceutical and Medicinal Reserach, 4(6), -. https://europub.co.uk/articles/-A-31531