Evaluation of the cariogenic and erosive potential of pediatric liquid analgesics: An in-vitro study
Journal Title: International Journal of Pharmaceutical and Medicinal Reserach - Year 2016, Vol 4, Issue 3
Abstract
Objective: The objective of the present study is to analyze the endogenous pH, viscosity and total sugar content in 20 commonly prescribed pediatric liquid analgesics. Study design: The pH of each medicine was determined using a digital pH meter (Elico pH meter), viscosity measured using a calibrated digital rotational viscometer (Brookfield viscometer) and sugar content in these medicines was measured using Fehlings method. Results : The pH values of all syrups tested are below critical value of 5.5 with lowest pH in Syr. Ibuprofen group with mean value of 3.98 , sucrose was seen to be maximum in Syr. Ibuprofen group in the mean concentration of 43.13% ± 0.25% and viscosity was found to be higher in Syr. Combiflam group with mean value of 897 cP. Conclusion: In summary, our study showed that most PLA tested had pH values below the critical value, high viscosity and high total sugar content all of which increase the medicines cariogenic and erosive potential. The Pedodontist has a major role in educating the people at various levels of the society about the ill effects of using certain PLAs.
Authors and Affiliations
K. Sowmya, V. Pranitha, K. S. Dwijendra, C. Pujita, G. Nagarjuna
Keywords
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- EP ID EP31517
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