Fatty Acid Binding Protein 3 (FABP3) Deficiency Does Not Impact on Feto-Placental Morphometry and Fatty Acid Transporters in Mice
Journal Title: Bioresearch Communications - Year 2015, Vol 1, Issue 2
Abstract
In most mammals, proper placentation along with its morphology is critical for fetal development and pregnancy success. Fatty acid binding protein 3 (FABP3) has been shown to regulate the transportation of polyunsaturated fatty acid (PUFA) to the fetus, but its impact on placental morphology and genetic alteration of fatty acid transporters in trophoblast cells is still unknown. Using mice model we found Fabp3 deficiency does not affect the morphology of placenta along with the gene of fatty acid transporters. FABP3 deficiency was also found to have no impact on the morphology of human trophoblast cells (BeWo cells) in in vitro study. Fatty acid transporter genes were also remains unaltered after FABP3 knockdown. Our study suggests that placenta may conserve its morphology and genetics although it has PUFAs deficiency.
Inhibition of CCR5 and CXCR4 prevents HIV infection
CCR5 and CXCR4 are chemokine receptors recognize by HIV to enter into the host cell. In this review, we focus on their biology, function and pivotal role in HIV-1 infection, and also, how HIV quasi-species change tropism...
Two Cases of Klinefelter Syndrome Identified by Quantitative Fluorescence PCR (QF-PCR) Method
Chromosomal aneuploidy is a common cause of genetic abnormality in humans and leading cause of pregnancy loss and congenital birth defects. Pregnancies with chromosomal aneuploidies that survive to term include trisomy 1...
In vitro evaluation of fungicides and plant extracts against pathogenic fungi of jute seeds
Two pathogenic fungi viz. Curvularia lunata (Wakker) Boedijn and Fusarium oxysporum Schlecht were isolated from different accessions of Corchorus capsularis L. collected from Bangladesh Jute Research Institute (BJRI). “B...
In vitro Efficacy of Plant Extracts on Seed Germination and Fungal Infection of Six Varieties of Wheat (Triticum aestivum L.)
The fungitoxicity of six plants extract viz., Allium sativum L., Azadirachta indica A. Juss., Citrus limon (L.) Burm. f., Datura metel L., Gynura procumbens Merr. and Thuja occidentalis L. were evaluated on seed germinat...
Mouse homologues of hepatitis C virus human entry factors inhibit the entry of HCV pseudoparticles (HCVpp) into human hepatoma cells
Hepatitis C virus (HCV) is a growing public health concern worldwide. No vaccine preventing HCV has yet been developed due to the hindrance of research on suitable small animal models. Moreover, it was known that human C...