INTERLEUKIN-6 GENE POLYMORPHISM IN FUNCTIONAL CONSTIPATION IN CHILDREN
Journal Title: International Journal of Scientific Pediatrics - Year 2022, Vol 5, Issue 5
Abstract
The authors studied the genetic marker C-174G of the IL-6 gene, the features of the distribution of the gene in functional constipation in children. The rarest genotype was homozygous for the C allele. In the group of healthy children, the C-genotype homozygous for the allele was more common than among patients. A positive association of the GG genotype (OR = 1.148) as well as the G allele (OR = 1.096) with functional constipation was shown. The presence of these allelic variants indicates an increased risk of developing functional constipation, the probability of a defect in the process of replacing guanine (G) with cytosine (C) is high.
Authors and Affiliations
Navruzova Shakar Istamovna Xamrayeva Dilnoza Razzakovna
Keywords
Related Articles
- EP ID EP709729
- DOI 10.56121/2181-2926-2022-5-05-10
- Views 62
- Downloads 0
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