Medicated chewing gum: modern approach to improve mucosal drug delivery system- a review
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2014, Vol 2, Issue 8
Abstract
In current years technological advancements have been made in the research and development of oral drug delivery systems. It is considered to be a potential and convenient modified release drug delivery system which can be used in pain relief medication, smoking cessation, travel sickness, freshening of breath, avert of dental caries, mitigation of xerostomia, vitamin or mineral companion etc. Medicated chewing gums are solid, single dose making with a base consisting mainly of gums that are intended to be chewed but not swallowed. It is a potentially valuable means of administering drugs either locally or systematically via, the oral cavity. Chewing gum known as gum base (insoluble gum base resin) contains elastomer, emulsifiers, fillers, waxes, antioxidants, softners, sweeteners, food colorings, add to flavor agents, and in case of medicated chewing gum, active contents. An In-vitro apparatus was specially designed and constructed for release testing of medicated chewing gums.
Authors and Affiliations
Rajesh Asija| Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur-302020, Rajasthan, India., Aakash Yadav| Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur-302020, Rajasthan, India., Sangeeta Asija| Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur-302020, Rajasthan, India., Sikander Ali Sheikh| Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur-302020, Rajasthan, India., Atul Sharma| Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur-302020, Rajasthan, India.
Keywords
Related Articles
- EP ID EP1514
- DOI -
- Views 389
- Downloads 25
DIETARY ANTIOXIDANTS TO PROP UP VIGOUR & VITALITY: AN OVERVIEW
One of the important objectives of modern health care, in addition to prevention of diseases, is the development of active treatments that control illnesses with minimum side effects to the body. Ayurvedic medicines, the...
A REVIEW ON IMMEDIATE RELEASE DRUG DELIVERY SYSTEM BY USING DESIGN OF EXPERIMENT
Tablet is the most popular among all dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; Sometimes immediate onset of action is required than conventional t...
AN OVERVIEW ON MORINGA OLEIFERA: A POTENTIAL MEDICINAL HERB
Moringa Oleifera tree is known as miracle tree, as an almost every part of this tree possesses product useful for humans. It is a multipurpose tree, used in very commonly in the spice, cosmetic oil, and as a medicinal us...
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF SOME 1,3,4-OXADIAZOLE DERIVATIVES WITH BENZOXAZOLE MOIETY
Synthesis of 1,3,4-oxadiazole derivatives has attracted considerable attention in view of therapeutic applications. In the presented research work, a series of novel 5-substituted-1,3,4-oxadiazole-2-thiol containing pipe...
A review on antihyperlipidemic activity of various herbal plants and various experimental animal models
Hyperlipidemia is a disorder of lipid metabolism which is major risk of coronary heart disease. Now day’s synthetic drugs have been associated with number of side effects but herbal medicines have lipid lowering and anti...