Mouth dissolving tablets: A current review of scientific literature

Abstract

The objective of this paper was to review the information about mouth dissolving tablets. Methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, mouth dissolving drug delivery systems (MDDDS) have acquired an important position in the market by overcoming previously encountered administration problems and contributing to extension of patent life. MDDDS have the unique property of rapidly disintegrating and/or dissolving and releasing the drug as soon as they come in contact with saliva, thus obviating the requirement of water during administration. This is seen to afflict nearly 35% of the general population and associated with a number of conditions, like parkinsonism, mental disability, motion sickness, unconsciousness, unavailability of water etc. To overcome such problems, certain innovative drug delivery systems, like ‘Mouth Dissolving Tablets’ (MDT) have been developed. These are novel dosage forms which dissolve in saliva within a few seconds, when put on tongue. Such MDTs can be administered anywhere and anytime, without the need of water and are thus quite suitable for children, elderly and mentally disabled patients. This article describes the existing techniques for fast dissolving oral preparation, highlights their manufacturing processes, evaluation parameters and future trends for these evolving forms. Such MDTs can be administered anywhere and anytime, without the need of water and are thus quite suitable for children, elderly and mentally disabled patients. The excipients that are currently used as well as those that are expected to be used for the future development of improved FDTs are described in the review paper.

Authors and Affiliations

Geetika Sharma, Rupinder Kaur, Sukhdev Singh, Ajay Kumar, Shivani Sharma, Ramandeep Singh, Yogesh Kumar

Keywords

Related Articles

Importance of Agni and its Impact on Human Body

Ayurveda is the ancient Indian system of life sciences and Medicine, its historicity going back to the Vedas. Its classical knowledge and practice is based on its own physics and biology, its unique pronature holistic...

Validated Chromatographic method for Estimation of CoQ10 in Bulk Drug and SelfNanoemulsifying Formulation

A simple, precise and sensitive RP-HPLC method was developed and validated for the routine analysis of CoQ10 in bulk drug and self-nanoemulsifying formulation. The analyte was quantified using column C18 which configur...

To evaluate the efficacy of Gritakumari (Aloe Vera Gel) in the management of Shushkakshipaka (Dry Eye Syndrome)

Background: The tear film is fundamental of the maintenance of the ocular surface. Deficiency in tear quantity or quality, which can be caused by low tear production or excessive tear evaporation, results in an unstabl...

Evaluation of the cariogenic and erosive potential of pediatric liquid analgesics: An in-vitro study

Objective: The objective of the present study is to analyze the endogenous pH, viscosity and total sugar content in 20 commonly prescribed pediatric liquid analgesics. Study design: The pH of each medicine was determin...

Preparation and drug release assessment of mesalazine matrix tablets

The major objective is to develop colon targeted drug delivery system by using Chitosan, Eudragit S 100 and Ethylcellulose and to compare the results obtained by three different carrier systems. Results obtained were f...

Download PDF file
  • EP ID EP31455
  • DOI -
  • Views 274
  • Downloads 2

How To Cite

Geetika Sharma, Rupinder Kaur, Sukhdev Singh, Ajay Kumar, Shivani Sharma, Ramandeep Singh, Yogesh Kumar (2013). Mouth dissolving tablets: A current review of scientific literature. International Journal of Pharmaceutical and Medicinal Reserach, 1(2), -. https://europub.co.uk/articles/-A-31455