NEBULIZATION THERAPY - A NOVEL APPROACH TO DRUG DELIVERY SYSTEM IN AYURVEDA
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 11
Abstract
The process of Nebulization involves a suspension of fine vaporized liquid droplets--otherwise known as aerosol--to administer fluids, oxygen and liquid medication directly to the respiratory system. Nebulizers are commonly used for treatment of cystic fibrosis, asthma, COPD and other respiratory diseases. Breakthroughs in the treatment of Asthma came in light with the introduction of Inhalation therapy (Nebulization / Aerosol mode of drug administration) in the conventional medicine. There are several plus points for through-the-lung delivery of medication. The lungs have a large surface area, so that absorption is fast and ample. Lungs are quite tolerant to foreign substances like powders of tobacco, smoke, and fragrances of a hundred types by common men. Lungs are much more permeable than skin, nasal mucosa or the gastro-intestinal tract. This mode of administration proves to be highly beneficial in saving life in acute life threatening condition such as “Status Asthmatics”. But wide range of toxic side effects of modern medicine confines its use as permanent remedy. Administration of drug through nasal route is highly prevalent also in Ayurveda. Since ancient time Acharays very well knew the importance and effectiveness of this route as they had said that“Nasa hi Shirsodvaram”. There are numerous variety of drugs mentioned in Ayurvedic text which can be administered through Nasal route, namely Nasya and Dhumrapana.There is no direct evidence that drug given through Nasya and Dhumrapana acts similar to that given through Nebulization technique. According to the demand of time Ayurvedic science also requires some modification to become more permissive and harmonize with ever-increasing diseases and their various presentations. Thus there is need to search Ayuurvedic formulations to be used for inhalation which are as effective as modern inhalation therapy and have least side effect and that can be useful in emergency condition. The clinical study was planned in two parts. The first part deals with preparation of drug, its standardization and antimicrobial study and second part deals with assessment of its efficacy in acute attack of Bronchial Asthma, and its comparison with the efficacy of modern medicine. The paper will discuss the method and material use for the preparation of Ayurvedic Nebulizer drug and its standardization.
Authors and Affiliations
Divya Kajaria , J. S. Tripathi , S. K. Tiwari
Keywords
Related Articles
- EP ID EP92496
- DOI -
- Views 111
- Downloads 0
ANALYTICAL STUDY OF CURCUMIN CONTENT IN DIFFERENT DOSAGE FORMS CONTAINING TURMERIC EXTRACT POWDER AND TURMERIC OLEORESIN
Different dosage forms namely tablets, capsules, creams and syrups were analysed for curcumin content, by the well-known spectrophotometric method. Turmeric extract powder was used as a source of curcumin in capsule and...
FORMULATION AND EVALUATION OF FAST DISSOLVING FILMS OF LORATADINE FOR SUBLINGUAL USE
Loratadine is a second generation orally administered non-sedative antihistamine used in the symptomatic relief of allergy such as hay fever (allergic rhinitis), urticarial (hives) and other skin allergies. In the work u...
QUANTITATIVE PHYTOCHEMICAL AND GC-MS ANALYSIS OF LEAF AND BARK EXTRACT OF DOLICHANDRONE ATROVIRENS
The present study deals with the quantitative phytochemical and GC-MS analysis of aqueous methanolic bark and leaf extract of Dolichandrone atrovirens. This study concerns the quantitative screening of total glycosides,...
FAST DISSOLVING TABLETS: A NEW ERA IN NOVEL DRUG DELIVERY SYSTEM
Fast dissolving tablets (FDTs) have received ever-increasing demand during the last decade and the field has become a rapidly growing area in the pharmaceutical industry. Fast dissolving tablets (FDTs) are those solid do...
FORCED DEGRADATION STUDIES: PRACTICAL APPROACH - OVERVIEW OF REGULATORY GUIDANCE AND LITERATURE FOR THE DRUG PRODUCTS AND DRUG SUBSTANCES
The Objective of the review article is to give a detailed description of the forced degradation studies as per the regulatory guidelines that are associated with various regulatory agencies. This article summarizes the c...