New tuberculosis vaccine to support tuberculosis elimination

Journal Title: Universa Medicina - Year 2018, Vol 37, Issue 2

Abstract

The Sustainable Development Goals have prioritized ending the epidemic of tuberculosis by 2030.(1) Around one-third of the world population is infected with Mycobacterium tuberculosis (MTBC), but is asymptomatic, a conditon known as latent TB.According to the global tuberculosis report, in 2017 there were 5-15% of 1.7 billion persons infected with MTBC, who will develop TB in their lives. Around 10% of latent TB will develop into active TB disease, with a higher risk in patients with immunodeficiencies such as HIV, undernutrition, diabetes mellitus, smoking, and habitual alcohol consumption. As a result there are annually an estimated 8.8 million new TB cases, with a TB mortality of 1.1 million and deaths from TB and HIV coinfection of 350 thousand cases.The World Health Organization has planned a number of strategies for TB elimination in the year 2030, such as developing rapid and accurate diagnostic tests, new regimens for the treatment of drug-susceptible or drug-resistant TB, prevention of transmission of M. tuberculosis through infection control, new vaccine candidates to prevent the development of TB, and to help improve the outcomes of treatment for TB disease.

Authors and Affiliations

Fransisca Chondro

Keywords

Related Articles

Age-related changes of malondialdehyde, body weight and organ weight in male mice

Introduction Aging is characterized by gradual impairment in all physiological functions. Increases in free radicals and changes in organ morphology occur with aging. The purpose of this study was to determine age-relate...

Combination of aerobic exercise and Hibiscus sabdariffa Linn. increased nitric oxide in rats

Background Hypertension and myocardial infarction account for the high rate of mortality globally. Hibiscus sabdariffa (HS) Linn. is rich in antioxidants and previous studies have demonstrated its anti-hypertensive effe...

The changing paradigm of dyslipidaemia management

The 2013 American College of Cardiology (ACC)/American Heart Association (AHA) guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults,(1) effected a change in the paradigm...

Regular condom use tends to decrease cervical lesions in resident-commercial sex workers in Sub-Saharan Africa

BACKGROUND Cervical lesions are abnormalities seen in tissues and cells examined from the uterine cervix. These abnormalities are on the increase and are ignored; thereby constituting major health problems in resident co...

Aloe vera extract reduces 8-oxo-2'-deoxyguanosine levels and improves total antioxidants in streptozotocin-induced diabetic rats

Background Diabetes mellitus is a chronic disease caused by lack of insulin production in the pancreas or by insulin resistance, the disease being characterized by elevated blood glucose levels. Hyperglycemia in diabete...

Download PDF file
  • EP ID EP382327
  • DOI 10.18051/UnivMed.2018.v37.85-87
  • Views 211
  • Downloads 0

How To Cite

Fransisca Chondro (2018). New tuberculosis vaccine to support tuberculosis elimination. Universa Medicina, 37(2), 85-87. https://europub.co.uk/articles/-A-382327